Allergic rhinitis
Allergic rhinitis
AllergicrhinitisItis an IgE mediated immunologic response of nasalmucosato air-bone allergens and is characterized bywaterynasaldischarge,nasalobstruction,sneezingand itching in the nose. This may also be associatedwithsymptomsof intheeyes,plateandpharynx.Twoclinical types have been rescognized:1.Seasonal. Symptoms appears in or around a particularseason when the pollens of particular plant, to whichthe patients is sensitive, are present in the air.2. Perennial. Symptoms are present throughout the year
Allergic rhinitis • It is an IgE mediated immunologic response of nasal mucosa to air-bone allergens and is characterized by watery nasal discharge, nasal obstruction , sneezing and itching in the nose. This may also be associated with symptoms of in the eyes, plate and pharynx. Two clinical types have been rescognized: 1. Seasonal. Symptoms appears in or around a particular season when the pollens of particular plant, to which the patients is sensitive, are present in the air. 2. Perennial. Symptoms are present throughout the year
Allergicrhinitis:AetiologyInhalant allergens are oftenthecausePollenfromthetrees and grasses,mouldspores,house dust,debrisfrominsectsorhouse miteare common offenders.Foodallergy is rarely an important cause.Geneticpredispositionplays an importantpart
Allergic rhinitis • Aetiology Inhalant allergens are often the cause. Pollen from the trees and grasses, mould spores, house dust, debris from insects or house mite are common offenders. Food allergy is rarely an important cause. Genetic predisposition plays an important part
Commen allergens·SpecificPollenfoodsDustmitesmilkFurryanimalseggsMoldspeanuts15KV30003wheatCockroachessoy·Stingingfish/shellfishinsectstreenuts
Commen allergens • Pollen • Dust mites • Furry animals • Molds • Cockroaches • Stinging insects • Specific foods ➢ milk ➢ eggs ➢ peanuts ➢ wheat ➢ soy ➢ fish/shellfish ➢ tree nuts 30003 30003 15KV 15KV 50U50U
Allergicrhinitis·Pathogenesis1.lnhaled allergens produce an important partspecificIgE antibody inthegeneticallypredisposed individuals. This antibody becomesfixed to thebloodbasophils ortissues mastcells.2.On subsequent exposure.Antigen combines withIgEantibody.This reactionproducesdegranulation of the mast of the cells withrelease ofseveralchemical mediators
Allergic rhinitis • Pathogenesis 1.Inhaled allergens produce an important part specific IgE antibody in the genetically predisposed individuals. This antibody becomes fixed to the blood basophils or tissues mast cells . 2.On subsequent exposure. Antigen combines with IgE antibody. This reaction produces degranulation of the mast of the cells with release of several chemical mediators