11. Suppositories and Inserts
11. Suppositories and Inserts
Contents 1. Suppositories Some factors of drug absorption from rectal suppositories 3. Suppository bases 4. Preparation of suppositories 5. Rectal suppositories 6. Vaginal suppositories 7. Packaging and storage 8. Vaginal inserts
Contents 1. Suppositories 2. Some factors of drug absorption from rectal suppositories 3. Suppository bases 4. Preparation of suppositories 5. Rectal suppositories 6. Vaginal suppositories 7. Packaging and storage 8. Vaginal inserts
1. Suppositories a Suppositories are solid dosage forms intended for insertion into body orifices where they melt, soften, or dissolve and exert local or systemic effects a Suppositories are commonly used rectally and vagina LIly and accasionally urethrally They have various shapes and weights
1. Suppositories ◼ Suppositories are solid dosage forms intended for insertion into body orifices where they melt, soften, or dissolve and exert local or systemic effects. ◼ Suppositories are commonly used rectally and vaginally and accasionally urethrally. They have various shapes and weights
a The shape and size of a suppository must be such that it can be easily inserted into the intended orifice without causing undue distension, and once inserted it must be retained for the appropriate period
◼ The shape and size of a suppository must be such that it can be easily inserted into the intended orifice without causing undue distension, ◼ and once inserted, it must be retained for the appropriate period