Mitochondrial dysfunction associated disordersJiangang Long,PH.D.Institute of Mitochondrial Biologyand MedicineXIl'AN Jiaotong University
Mitochondrial dysfunction associated disorders Jiangang Long, PH.D. Institute of Mitochondrial Biology and Medicine XI’AN Jiaotong University
MitochondrialdysfunctionassociateddisordersMitochondrial dysfunction-related diseases:a class of diseasesassociated with mitochondrial oxidative damage and energyimpairment, excluding mitochondrial hereditary diseases.Alzheimer'sdisease(AD)Parkinson's disease(PD)Type2diabetes (TD)Age-relatedmaculardegeneration(AMD)
Mitochondrial dysfunction associated disorders Mitochondrial dysfunction-related diseases: a class of diseases associated with mitochondrial oxidative damage and energy impairment, excluding mitochondrial hereditary diseases. ⚫ Alzheimer’s disease (AD) ⚫ Parkinson’s disease (PD) ⚫ Type 2 diabetes (TD) ⚫ Age-related macular degeneration (AMD) ⚫
Alzheimer's disease,AD阿尔茨海默症
Alzheimer’s disease, AD 阿尔茨海默症
Keypoints Discovery and symptoms of AD, incidence(China)Pathological characteristicsAPP and AβMitochondria and ADOxidative damageDynamicchangesMitochondrialnutrients
Key points Discovery and symptoms of AD, incidence (China) Pathological characteristics APP and Aβ Mitochondria and AD ◼ Oxidative damage ◼ Dynamic changes ◼ Mitochondrial nutrients
Alzheimer's Disease（(AD）First described by German psychiatrist andneuropathologist Alois Alzheimer in 1906The most common form of dementiaPatientsshowed progressive cognitive decline,including memory, thinking, analysis and judgmentvisual space.emotional and other obstaclesAlzheimer'sdiseaseisthemostcommonneurodegenerative disease in the elderlyDr.Alzheimer
Alzheimer’s Disease (AD) Dr. Alzheimer • First described by German psychiatrist and neuropathologist Alois Alzheimer in 1906 • The most common form of dementia • Patients showed progressive cognitive decline, including memory, thinking, analysis and judgment, visual space, emotional and other obstacles. • Alzheimer's disease is the most common neurodegenerative disease in the elderly