CHATER 8 The replication of na Teaching Arrangement Watch animation-Understand replication a Go through structural tutorial- Experience the BEAUTY of the nature a Lecture-comprehensive understanding of Chapter 8 Summary and highlight Key points
Teaching Arrangement ◼ Watch animation-Understand replication ◼ Go through structural tutorialExperience the BEAUTY of the nature ◼ Lecture-comprehensive understanding of Chapter 8 ◼ Summary and highlight Key points CHAPTER 8 The replication of DNA
CHATER 8 The replication of na The Chemistry of DNA Synthesis >The Mechanism of DNA Polymerase > The Replication Fork The Specialization of DNA General Polymerases DNA Synthesis at the Replication Fork > Initiation of DNA Replication > Binding and Unwinding Detailed >Finishing Replication
The Chemistry of DNA Synthesis ➢ The Mechanism of DNA Polymerase ➢ The Replication Fork ➢ The Specialization of DNA Polymerases ➢ DNA Synthesis at the Replication Fork ➢ Initiation of DNA Replication ➢ Binding and Unwinding ➢ Finishing Replication General Detailed CHAPTER 8 The replication of DNA
CHATER 8 The replication of na The first part describes the basic chemistry of DNA synthesis and the function of the dna polymerase 劣溪字 Wuhan University
The first part describes the basic chemistry of DNA synthesis and the function of the DNA polymerase CHAPTER 8 The replication of DNA
CHAPTER 8 The replication of ona The chemistry of dNa DNA synthesis requires deoxynucleoside triphosphates and a primer:template junction DNA is synthesized by extending the 3 end of the primer Hydrolysis of pyrophosphate(Ppi)is the driving force for DNA synthesis 劣溪字 Wuhan University
The Chemistry of DNA CHAPTER 8 The replication of DNA ➢ DNA synthesis requires deoxynucleoside triphosphates and a primer:template junction ➢ DNA is synthesized by extending the 3’ end of the primer ➢ Hydrolysis of pyrophosphate (PPi) is the driving force for DNA synthesis
base(A, G, C, or T) HO一P—0—P-0—P—0—CH OH b annealed primer growing end of DNA 50 OH 3 template strand Ac GTCGACGIT C GAco IT C GACGT 3 HO ⊙5 dsDNA SSDNA Figure 8-3 Substrates required for DNA synthesis
Figure 8-3 Substrates required for DNA synthesis