Molecular Biology of the Gene, 5/E Watson et al (2004) Part I: Chemistry and Genetics Part Ii: Maintenance of the Genome Part III: Expression of the Genome Part IV: Regulation Part v: methods 4/3/05 肃博来字
Molecular Biology of the Gene, 5/E --- Watson et al. (2004) Part I: Chemistry and Genetics Part II: Maintenance of the Genome Part III: Expression of the Genome Part IV: Regulation Part V: Methods 4/3/05
ch 12: Mechanisms of Transcription 口ch13: RNA Splicing ch 14: Translation ch 15: The Genetic code 4/3/05 刻博来字 Wuhan Universit
Ch 12 : Mechanisms of Transcription Ch 13 : RNA Splicing Ch 14 : Translation Ch 15 : The Genetic code 4/3/05
Molecular Biology course CHAPTER 13 RNA Splicing @或属来字 Wuhan Universi
CHAPTER 13 RNA Splicing •Molecular Biology Course
promoter region itron 1 genomIc DNA exon 1 transcription noncoding 5 leader reqion 4 pre-mRNA 5 3 Primary transcript splIcing spliced mRNA 5匚 3 1234 Figure 13-1
Figure 13-1 Primary transcript
Most of the eukaryotic genes are osage(嵌合体), consisting of intervening sequences separating the coding sequence Exons(外显子): the coding sequences 工 introns(内含子): the intervening sequences a RNA splicing: the process by which introns are removed from the pre mRNA Alternative splicing(可变剪接):some pre-mRNAs can be spliced in more than one way, generating alternative mRNAS. 60%o of the human genes are spliced in this manner
Most of the eukaryotic genes are mosaic (嵌合体), consisting of intervening sequences separating the coding sequence ◼ Exons (外显子): the coding sequences ◼ Introns (内含子) : the intervening sequences ◼ RNA splicing: the process by which introns are removed from the premRNA. ◼ Alternative splicing (可变剪接): some pre-mRNAs can be spliced in more than one way , generating alternative mRNAs. 60% of the human genes are spliced in this manner