武汉大学生命科学学院:《分子生物学》(英文版)Part II:Maintenance of the Genome CHAPTER11 Site-Specific Recombination & Transposition of DNA ?Molecular Biology Course

Although DNA replication, repair, homologous recombination occur with high fidelity to ensure the genome identity between generations, there are genetic processes that rearrange DNA sequences and thus lead to a more dynamic genome structure Two classes of genetic recombination for DNA rearrangement: • Conservative site-specific recombination (CSSR): recombination between two defined sequence elements • Transpositional recombination (Transposition): recombination between specific sequences and nonspecific DNA sites
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