clinical features chronic ☆ acute pallor aRa⊥gor、 jaundice yperpyrex1a、 splenomegaly sore waist cholelithiasis HEmoglobinuria cRaplastic crisis JAundice、 anaemia
clinical features ❖chronic pallor 、 jaundice 、 splenomegaly cholelithiasis aplastic crisis ❖acute algor、 hyperpyrexia、 sore waist hemoglobinuria jaundice、 anaemia
laboratory examination 8 Increased rbc destruction Reduced RBC life spa an g. Indirect hyperbilirubinemia .o Erythroid hyperplasia %o Reticulocytosis %o Erythroblasts, anisopoikilocytosis, spherocytes in blood smear g Erythroid hyperplasia in bone marrow
laboratory examination ❖ Increased RBC destruction ❖ Reduced RBC life span ❖ Indirect hyperbilirubinemia ❖ Erythroid hyperplasia ❖ Reticulocytosis ❖ Erythroblasts, anisopoikilocytosis, spherocytes in blood smear ❖ Erythroid hyperplasia in bone marrow
②
diagnosis and differential diagnosis %hemolysis or not? ☆ type of hemolysis g another anemia? %another jaundice with anemia? % another jaundice without anemia?
diagnosis and differential diagnosis ❖hemolysis or not? ❖type of hemolysis ❖another anemia? ❖another jaundice with anemia? ❖another jaundice without anemia?