病理 °肉眼:肾脏体积增大 LM:弥漫性毛细血管内增生性肾炎 IF:IgG及C3呈粗颗粒状沿毛细血管壁和 或系膜区沉积 EM:肾小球上皮下驼峰状大块电子致密 物沉积
病理 • 肉眼：肾脏体积增大 • LM：弥漫性毛细血管内增生性肾炎 • IF：IgG及C3呈粗颗粒状沿毛细血管壁和/ 或系膜区沉积 • EM：肾小球上皮下驼峰状大块电子致密 物沉积
动式 This glomerulus is hypercellular and capillary loops are poorly defined. This is a type of proliferative glomerulonephritis known as post-streptococcal glomerulonephritis
This glomerulus is hypercellular and capillary loops are poorly defined. This is a type of proliferative glomerulonephritis known as post-streptococcal glomerulonephritis
厘ND The hypercellularity of post-streptococcal glomerulonephritis is due to increased numbers of epithelial, endothelial, and mesangial cells as well as neutrophils in and around the capillary loops This disease may follow several weeks after infection with certain strains of group A beta hemolytic streptococci Patients typically have an elevated anti-streptolysin O(ASO)titer
The hypercellularity of post-streptococcal glomerulonephritis is due to increased numbers of epithelial, endothelial, and mesangial cells as well as neutrophils in and around the capillary loops. This disease may follow several weeks after infection with certain strains of group A beta hemolytic streptococci. Patients typically have an elevated anti-streptolysin O (ASO) titer
INDE Post-streptococcal glomerulonephritis is immunologically mediated, and the immune deposits are distributed in the capillary loops in a granular, bumpy pattern because of the focal nature of the deposition process
Post-streptococcal glomerulonephritis is immunologically mediated, and the immune deposits are distributed in the capillary loops in a granular, bumpy pattern because of the focal nature of the deposition process
BM By electron microscopy, the electron dense immune deposits of post-streptococcal glomerulonephritis are predominantly subepithelial, as seen here with a large subepithelial hump"at the right of the basement membrane(BM). The capillary lumen is filled with a PMN whose nuclear lobes and cytoplasmic granules are visible
By electron microscopy, the electron dense immune deposits of post-streptococcal glomerulonephritis are predominantly subepithelial, as seen here with a large subepithelial "hump" at the right of the basement membrane (BM). The capillary lumen is filled with a PMN whose nuclear lobes and cytoplasmic granules are visible