日 R结构 英文名 中文名 缩写引 酸性氨基酸 -CH>COOH Aspartic acid 天冬氨酸 D,Asp 3.0 (天冬) E,Glu -(CH2)2C00H Glutamic acid 谷氨酸 3.2 (谷) 碱性氨基酸 K,Lys -(CH2)4NH2 Lysine a 赖氨酸 9.8 (赖) Arginine 精氨酸 R,Arg 10.8 (精) Histidine H,His 组氨酸 7.6 (组)
R结构 英文名 中文名 缩写 PI (等电点) 酸性氨基酸 -CH2COOH Aspartic acid 天冬氨酸 D,Asp (天冬) 3.0 -(CH 2 ) 2COOH Glutamic acid 谷氨酸 E,Glu (谷) 3.2 碱性氨基酸 -(CH2)4NH2 Lysine a 赖氨酸 K,Lys (赖) 9.8 Arginine 精氨酸 R,Arg (精) 10.8 Histidine 组氨酸 H,His (组) 7.6
Stereochemistry of a-Amino Acids EST ABF COOH CHO COOH H-N H H H COOH CHO COOH H2N H HO H H2N H CH3 CH2OH R (S)-alanine L-(-)-glyceraldehyde an L-amino acid (L-alanine) (S)configuration
Stereochemistry of -Amino Acids
L-amino acids are the natural form found in proteins "CORN"to the left L-amino acid “CDRN”to the right=D-amino acid PROTEINS ARE LEFTISTS!! Amino acids are tetrahedral structures
Properties of Amino Acids High melting points,over 200C More soluble in water than in ether. Larger dipole moments than simple acids or simple amines. Less acidic than most carboxylic acids, less basic than most amines. pK3=10 HN-CH-8o pK=12 R
Properties of Amino Acids ❖High melting points, over 200C ❖More soluble in water than in ether. ❖Larger dipole moments than simple acids or simple amines. ❖Less acidic than most carboxylic acids, less basic than most amines. H3 N CH R C O O + _ pKa = 10 pKb = 12
水林孔 R3:氨基酸的反应性质 里 Zwitterion and Isoelectric Point Reaction with Ninhydrin茚三酮 Esterification Acylation
R3:氨基酸的反应性质 ❖Zwitterion and Isoelectric Point ❖Reaction with Ninhydrin茚三酮 ❖Esterification ❖Acylation