I.HemodynamicsBlood flowQ=△P/R= (P1-P2)/RQ2PAPFlow=FAlA2r=radiusCopyight2002,Elsevir Science (USA),Allinighsresed
Blood flow Q= ΔP/R = (P1-P2)/R I. Hemodynamics
Q: cardiac output, 5 L/minQ= PA/RR: total peripheral resistancePA: aortic pressureRIGHTLEFTHEARTWNGTotal PeripheralVascularBRAINResistance (TPVR)Parallelsystem:1/TPVR=1/R,+1/R..Ponal验ThusRisalwayslessthananyindividual resistanceLIVERSPLEENSerial systemRou=R,+R.KIDNEYMUSCLESThusRuis alwayslargerthanCross sectional area(A)anyindividualresistanceofall open capillaries(Eg.8-1):SKINA=(10/(10)=0.1mFATBONE
Q: cardiac output, 5 L/min R: total peripheral resistance PA: aortic pressure Q= PA /R
ResistanceofbloodflowPoiseuille Law: Q=TT△Pr4/8nLd=11ml/min:. R= 8 nL / Tr4d=2P =16ml/min100mmHgd=4Q= △P/ R256ml/minAn: viscosityr: radius of the vesselOSmallvesselL: length of the vesselBLargevesselr (radius) : main determinant of blood flow
Resistance of blood flow Poiseuille Law: Q=πΔPr4 /8ηL η: viscosity r: radius of the vessel L: length of the vessel ∴ R= 8 ηL / πr 4 Q= ΔP/ R r (radius) : main determinant of blood flow
Il.Arterial blood pressureBlood pressure (BP)is the pressure ofcirculating blood on the walls of blood vesselsDIAGNOSTECNAISSystolicpressure(maximumSYSDIAduring one heart beat) ;0/PDiastolic pressure(minimum in between two heartAsphygmomanometerbeats).adeviceusedformeasuringarterialpressure
II. Arterial blood pressure Blood pressure (BP) is the pressure of circulating blood on the walls of blood vessels. A sphygmomanometer a device used for measuring arterial pressure Systolic pressure (maximum during one heart beat) ； Diastolic pressure (minimum in between two heart beats)
1.QualificationsStiffarteriesElasticarteriesVolume of circulatingbloodHeart pumping (power)+1Peripheral ResistancezSystolic/pulsepressureySystolic/pulsepressureDiastolicflow习DiastolicflowElasticity of aorta+心and arteries
1. Qualifications ④ Elasticity of aorta and arteries ② Heart pumping (power) ③ Peripheral Resistance ① Volume of circulating blood