Expression Why two types of polymorphic MhC genes are needed? DC,B,MΦ Nucleated celIs MHC II MHC I TCR TCR CD4T T CD8+ T
Why two types of polymorphic MHC genes are needed? DC, B, MΦ Nucleated cells Expression
Expression Microbe Production CD4+ NK cell T cell of IFN-y The expression of MHC IFN-Y molecules is increased by Resting APC (low MHC cytokines produced expression during Cytokine-mediated both innate and adaptive cass‖MHC expression on APCs Immune responses Activated APC Enhanced (high MHC antigen expression presentation IFN-a,IFNβ MHCI IFN-Y Enhanced IFN-Y MHCII T cell response et al: Cellular and Molecular Immunology, 7e ht@2012,2007,2005,2003,2000,1997,1994,1991 by saunders, an imprint of El
The expression of MHC molecules is increased by cytokines produced during both innate and adaptive immune responses. IFN-α, IFN-β , IFN-γ MHC I IFN-γ MHC II Expression