EpidemiologyaaoNatural InfectionProtectinglevelVaccinationInfectionvaccinationTim eDivision of InfectiolseasesAnd Gastroenterolog
Epidemiology Vaccination Natural Infection Protecting level Tim e Antibody level Infection vaccination Division Of Infectious Diseases And Gastroenterology
EpidemiologyEpidemiological FeaturesPriortotheuseofvaccineAfter theuse of vaccineMajorepidemics:500-1000Morbidity9.5 in1990Mildepidemics:400(1/100000)Peak seasonInwinterand springInany time of a yearMajorepidemicsappearbyEpidemiccycledisappeared,Epidemiccycle2-4yr intervalsSporadiccasesincreasedAge6m-5y(98%<10y）Below6m and teenageTypicalcasesAtypical casesincreasedClinicalseveremanifestationsmildmanifestationsmanifestationsless complicationsmore complicationsrarely deathhigh mortalityDivision Of Infectious Diseases And Gastroenterology
Prior to the use of vaccine After the use of vaccine Morbidity (1/100000) Major epidemics: 500-1000 Mild epidemics: 400 9.5 in1 990 Peak season In winter and spring In any time of a year Epidemic cycle Major epidemics appear b y 2-4yr intervals Epidemic cycle disappeared, Sporadic c ases increased Age 6 m-5y (98%<10y) B e l o w 6 m and teenage Typical cases Atypical cases increased Clinical manifestations severe manifestations more complications mild manifestations less complications high mortality rarely death Epidemiology Epidemiological Features Division Of Infectious Diseases And Gastroenterology
r PathogenesiseoAn福Division Of Infectiopenterologi
Division Of Infectious Diseases And Gastroenterology
PathogenesisaceadbaRespiratoryepitheliumfesoiratoryepithelurARegional lymph nodesregional lymph nodesLymphaticIncubationperiodPrimary viremia030OOOmononuclearphagocytic09stemSecond virimiasecondaryviremiaApparentm anifestationsRespiratory tract,Gconjunctiva,skin,etcVirus eliminationDivision Of Infectious Diseases And Gastroenterology
Apparent m anifestations Pathogenesis Respiratory tract, conjunctiva, skin,etc Virus elimination Respiratory epithelium regional lymph nodes Incubation period Primary viremia mononuclear phagocytic system secondary viremia Division Of Infectious Diseases And Gastroenterology
Pathology8>Division of InfectiouAnd Gastroenterologi
Division Of Infectious Diseases And Gastroenterology