Really?Matter OMs ■有机物仅在地球存在? 3500 ←3000 ●2014年在星际空间发现直链有机 2500 物;在银河系中心附近恒星形成 2000 区发现2-甲基丙腈。 1500 如 ●组成元素:C,H,0,N,X 1000 500 ●2006.12.2:W.G.Richards 19001945 30,009,658种 1970 19992006 年代 新化合物种类 ■有机分子有多少? Over 50 million carbon-containing (organic)compounds are known so far. ●超过一亿个有机分子被制备,其中绝大是药物化学研发; ●最大分子数据库(GDB-17)化合物库1664亿(<17C,N,0,S)
Really? Matter & OMs 有机物仅在地球存在? 2014年在星际空间发现直链有机 物;在银河系中心附近恒星形成 区发现2-甲基丙腈。 组成元素:C, H, O, N,X 2006.12.2: W.G. Richards 30,009,658种 有机分子有多少? Over 50 million carbon-containing (organic) compounds are known so far. 超过一亿个有机分子被制备,其中绝大是药物化学研发; 最大分子数据库(GDB-17) 化合物库1664 亿(<17 C,N,O,S)
Some organic chemicals 3M?Matter,Material Molecule DNA Medicines .Active Pharmaceutical Ingredients Excipients赋形剂 Fuels Materials Essential oils Pigments
Some organic chemicals DNA Essential oils Medicines •Active Pharmaceutical Ingredients •Excipients赋形剂 Materials Fuels Pigments 3M? Matter, Material, Molecule
胭脂电cochne insects 刺是(层状仙人掌 pear cac nicotine vitamin C carmine morphine CH2OH OH N-CH3 HCOHO. glucose COOH CH3 H OH HO OH OH OH OH Tobacco contains nicotine,an addictive alkaloid. Rose hips contain vitamin C,essential for preventing scurvy. The red dye carmine comes from cochineal insects,shown on a prickyrcactus. 胭脂T Opium poppies contain morphine,a pain-relieving,addictive alkalon
胭脂虫 cochineal insects 棘刺梨 (扇状) 仙人掌 prickly pear cactus 玫瑰果 Rose hips Tobacco contains nicotine, an addictive alkaloid. Rose hips contain vitamin C, essential for preventing scurvy. The red dye carmine comes from cochineal insects, shown on a prickly pear cactus. Opium poppies contain morphine, a pain-relieving, addictive alkaloid. 胭脂红
Some organic chemicals... H5C6 0三 CH3 -Taxol was first isolated (1962)from the bark of the Pacific yew tree(短叶紫杉). Taxol -It is produced today by semisynthesis from a 紫杉醇,红豆杉醇 precursor found in abundance in the needles and twigst嫩枝. >Taxol or paclitaxel used to treat breast and ovarian cancers. >Taxol blocks the division of the mitotic spindle resulting in the arrest of cell replication and cell death.有丝分裂纺锤体
Some organic chemicals… Taxol was first isolated (1962) from the bark of the Pacific yew tree(短叶紫杉). It is produced today by semisynthesis from a precursor found in abundance in the needles and twigs嫩枝. Taxol or paclitaxel used to treat breast and ovarian cancers. Taxol blocks the division of the mitotic spindle resulting in the arrest of cell replication and cell death. 有丝分裂纺锤体 紫杉醇,红豆杉醇 H5C6 N H O O C6H5 OH O O O O OH O O O CH3 O O H5C6 HO Taxol
-Millions of aspirin tablets are sold in the world each year. -An extract from willow bark,a precursor to modern aspirin,was used in the 1800's. -Book:Aspirin and related drugs 2004 前体
Aspirin Millions of aspirin tablets are sold in the world each year. An extract from willow bark, a precursor to modern aspirin, was used in the 1800’s. Book: Aspirin and related drugs 2004 前体