ThyroidGlandFunctionSynthesize,store,and releaseTandTintocirculationTisthemajorproductTisconvertedfromTyintheperipheraltissues
Thyroid Gland Function • Synthesize, store, and release T4 andT3 into circulation • T4 is the major product • T3 is converted from T4 in the peripheral tissues
Function of ThyroidHormone.Neurodevelopmental effect·CellularMetabolism· Protein, Lipid, &Glucose Metabolism·Growth and Development
Function of ThyroidHormone • Neurodevelopmental effect • Cellular Metabolism • Protein, Lipid, & GlucoseMetabolism • Growth and Development
Function:NeurodevelopmentalEffectPerinatalandpostnatalmaturationofbrainretina,andcochlea（耳蜗·T,directly promotes neural differentiation
Function: Neurodevelopmental Effect • Perinatal and postnatal maturation of brain, retina, and cochlea（耳蜗） • T3 directly promotes neural differentiation
Differentiation.maturition of infantpallium（大脑皮层）Pregnant 2moformationPregnant 5moDifferentiationpeak period ofLate foetal periodproliferation,---8mo after birthdifferentiation andmaturationUp to 3yrdifferentiation finishedAttention:thyroid hormone is essentialforthis process
Differentiation,maturition of infant pallium（大脑皮层） Pregnant 2mo Pregnant 5mo Late foetal period -8mo after birth Up to 3yr formation Differentiation peak period of proliferation, differentiation and maturation differentiation finished Attention: thyroid hormone is essential for this process
Function:CellularMetabolism·Stimulates the rate ofcellular oxidationincreased oxygen consumption, liberationofcarbon dioxide(CO,),and production ofheatWorks by affecting the synthesis ofmembranous sodium and potassiumATP-ases
Function: CellularMetabolism • Stimulates the rate of cellular oxidation increased oxygen consumption, liberation of carbon dioxide(CO2 ), and production ofheat • Works by affecting the synthesis of membranous sodium and potassium ATP-ases