2.Anchoring junction Contain cytoskeleton,cell-cell or cell-ECM; Widely distributed in the tissues,particularly rich in the tissue needed to withstand the mechanical stress. Adhesion belt Adhering Cell-cell junction (Actin) Adhesion plaque Cell-ECM Anchoring junction Desmosome Desmosome Cell-cell junction (IF) Hemidesmosome Cell-ECM 11 This document is produced by trial version of Print2Flash.Visit www.print2flash.com for more information
Anchoring junction cytoskeletal plasma membranes filaments CELL 1 CELL 2 extracellular matrix intracellular transmembrane anchor proteins adhesion proteins Transmembrane adhesion proteins link the cytoskeleton to extracellular structures This document is produced by trial version of Print2Flash.Visit www.print2flash.com for more information
2.1 Adhesion belt Position:Beneath tight junction Composition: 1)Transmembrane adhesion protein- Cadherin; 2)Intracellular anchor protein -a,B,y catenin,vinculin,a-actinin; 3)Cytoskeleton-actin. Function:Maintain cell morphology and tissue integrity,affect morphogenesis in the development. 13 This document is produced by trial version of Print2Flash.Visit www.print2flash.com for more information