遵义医科大学：《医学免疫学》课程教学资源（PPT专题课件）CAR-T肿瘤免疫治疗进展 Chimeric antigen receptor-modified T cell（主讲人：刘白南）

12 第四代CAR: 同时表达细胞因子，改善TME 4th generation CAR Amored CAR-T

第四代CAR: 同时表达细胞因子，改善TME

L-12 CD3 Co-stimulator 1 CD3 Co-stimulator 2 1st generation CAR 2nd generation CAR scFv-CD3 scFv-CD28-CD3ζ (C0S) (4-1B8) (0X-40 3rd generation CAR 4th generation CAR scFv-CD28-4/1BB-CD3 Amored CAR-T