Octameric histone core DNA HI histone 10 nm Histone octamer H1 histone Nucleosome
core histones linker DNA of nucleosome beads-on-a-string" nucleosome includes form of chromatin *200 nucleotide NUCLEASE DIGESTS LINKER DNA released nucleosome 11 nm core particle DISSOCIATION WITH HIGH CONCENTRATION OF SALT B Ss 146-nucleotide-pair histone core DNA double helix DISSOCIATION H2A
中国科学院上海生化与细胞所2002年招收硕士研究 生分子遗传学入学考试: 简述真核细胞内核小体与核小体核心颗粒的结构
中国科学院上海生化与细胞所2002年招收硕士研究 生分子遗传学入学考试： 简述真核细胞内核小体与核小体核心颗粒的结构
3、染色体的包装—超螺旋结构
3、染色体的包装—超螺旋结构
DNA double nwwwwwwwwn+ nm helix Figure 19.20 The 30 nm fiber may have a helical dnA double helⅸ coil of 6 nucleosomes per turn, organized radially 11 nm Axis of con a-string form of chromatin 6.8:I Nucleosome(10 nm fiber) Chromatin fiber of 33333 nucleosomes 40:I Extended section of 00 300nm 000 Condensed section of chromosome 700nm Loops II 8000:l chror m解 Meta 1400nr
6.8:1 40:1 1000: 1 8000:1 DNA double helix Nucleosome (10 nm fiber) 30 nm Fiber Loops I Loops II chromosome