Lecture3(10) The endogenous pathway of antigen processing and presentation (10 min)(ll)The exogenouspathway of antigen processingand presentation (10min)(12)Thestructureofantibodies (15min)(13) The structure, function, distribution and relative abundance of the five major classes of antibodies (15 min)三教学重点与难点教学重点1.(1)Innate and adaptive immune system(2) MHCclassIandclassIImolecules(3) Five main classes of antibodies2.教学难点(1)The differences between innate and adaptive immune system北(2)The different types of antigens and their respective function(3)Structural and functional difference between MHC classI and classIImolecules(4)Endogenous and exogenous antigen presentation pathways
Lecture 3 (10) The endogenous pathway of antigen processing and presentation (10 min) (11) The exogenous pathway of antigen processing and presentation (10 min) (12) The structure of antibodies (15 min) (13) The structure, function, distribution and relative abundance of the five major classes of antibodies (15 min) 三、教学重点与难点 1．教学重点 (1) Innate and adaptive immune system (2) MHC class I and class II molecules (3) Five main classes of antibodies 2.教学难点 (1) The differences between innate and adaptive immune system (2) The different types of antigens and their respective function (3) Structural and functional difference between MHC class I and class II molecules (4) Endogenous and exogenous antigen presentation pathways
四、教学方法选择1.理论课堂教学A.多媒体教学：（简要列出本章节多媒体教学设计特点及优势）(l)PowerPoint slidesforcontentdisplay(2)Videoclip aboutadaptiveimmunesystem(3) video clip about antibody structureB.互动教学：（根据实际情况列出案例/实例讨论、分析讨论、分组讨论、翻转课堂等互动教学内容标题）(l) On-screen multiple-choices quiz at the end of each section during the class(2) Discussion about the roles of MHC molecules the potential outcome during a virus pandemic2.实验课教学Not applicable.五、更新或补充内容提要课后总结：按照实际进度对知识点分详略进行讲解
四、教学方法选择 1.理论课堂教学 A.多媒体教学：（简要列出本章节多媒体教学设计特点及优势） (1) PowerPoint slides for content display (2) Video clip about adaptive immune system (3) Video clip about antibody structure B.互动教学：（根据实际情况列出案例/实例讨论、分析讨论、分组讨论、翻转课堂等互动教学内容标题） (1) On-screen multiple-choices quiz at the end of each section during the class (2) Discussion about the roles of MHC molecules the potential outcome during a virus pandemic 2.实验课教学 Not applicable. 五、更新或补充内容提要 课后总结：按照实际进度对知识点分详略进行讲解
Emphasizethe key components of Antigen,MHC and Antibody六、复习思考题(1)Outline the overall phases in a specific immune response(2)Summarize the general features of adaptive/acquired immunity. How is adaptive immunity different from innateimmunity?(3) Define antigen and immunogen(4)What are the main categories of antigens based on their chemistry and function?(5) How do shape, size and complexity contribute to antigenicity?(6)What is major histocompatibility complex?Explain howit participates in immune reactions(7)Why do we need different pathways for antigen presentation?七、学习资源、课外自主学习参考(可以列出供学生进一步学习、拓展本章节内容的网站、著作、期刊的名称及内容等）《医学免疫学》
Emphasize the key components of Antigen, MHC and Antibody 六、复习思考题 (1) Outline the overall phases in a specific immune response (2) Summarize the general features of adaptive/acquired immunity. How is adaptive immunity different from innate immunity? (3) Define antigen and immunogen (4) What are the main categories of antigens based on their chemistry and function? (5) How do shape, size and complexity contribute to antigenicity? (6) What is major histocompatibility complex? Explain how it participates in immune reactions (7) Why do we need different pathways for antigen presentation? 七、学习资源、课外自主学习参考 (可以列出供学生进一步学习、拓展本章节内容的网站、著作、期刊的名称及内容等) 《医学免疫学》
Basic Immunology:Functions and Disorders of the Inmune System
Basic Immunology: Functions and Disorders of the Immune System
苏州大学医学部药学院授课教案授课教师：郑毅然授课日期：2021年3月31日药学课程名称Microbiology and immunology(英文)所属学科药学全英班Foundations in Microbiology 1Oth Edition教材名称授课年级Kuby Immunology 7th Edition二年级授课章节Tcelldevelopment,activationanddifferentiation授课时间150分钟教学目标：含知识目标、技能（能力）目标1.知识目标：(1)Know the basic steps involved in the_T cell development(2)Understand the positive selection and negative selection steps in the T cell development and grasp the significanceof havingboth(3)Know the signals required for T cell activation and themolecules involved(4)Knowthe main subsets ofT cells and their respectivefunction2.技能（能力）目标：(1)Learn thebasic immunology terms in English(2)Improve theof scientificEnglishreading,listening,speakingand writingI授课内容（依据教学大纲）及时间分配Lecture l:(1)Overviewof tissues and organsrequired for T cell development (1omin)(2) Early thymocyte development (10 min)(3)The origin of T cell receptor diversity(30 min)Lecture. 2:
苏州大学医学部药学院授课教案 授课教师：郑毅然授课日期：2021年3月31日 课程名称 Microbiology and immunology（英文） 所属学科 药学 教材名称 Foundations in Microbiology 10th Edition Kuby Immunology 7th Edition 授课年级 药学全英班 二年级 授课章节 T cell development, activation and differentiation 授课时间 150分钟 一、教学目标：含知识目标、技能（能力）目标 1.知识目标： (1) Know the basic steps involved in the T cell development (2) Understand the positive selection and negative selection steps in the T cell development and grasp the significance of having both (3) Know the signals required for T cell activation and the molecules involved (4) Know the main subsets of T cells and their respective function 2.技能（能力）目标： (1) Learn the basic immunology terms in English (2) Improve the reading, listening, speaking and writing of scientific English 二、授课内容（依据教学大纲）及时间分配 Lecture 1: (1) Overview of tissues and organs required for T cell development (10 min) (2) Early thymocyte development (10 min) (3) The origin of T cell receptor diversity (30 min) Lecture 2: