苏州大学医学部药学院授课教案授课教师：王媛授课日期：2021年3月19日药学课程名称所属学科Microbiologyandimmunology(英文)药学全英班Foundations in Microbiology 1oth Edition教材名称授课年级Kuby Immunology 7th Edition二年级授课章节Innate immunity授课时间150分钟教学目标：含知识目标、技能（能力）目标1.知识目标：(1) To understand the principles of host defense and immune responses(2) To understand the process and functions of innate immunity (inflammation, phagocytosis, interferons)(3) To understand and grasp the function and mechanism of complement system2.技能（能力）目标：结合实验课程目标二授课内容（依据教学大纲）及时间分配Lecturel:(1) The characteristics of basic host defenses(5min)(2) Introduction of three lines of host defense (5 min)(3)First line of host defense: different barrierscomponents,structure and functions(4min)(4)Introduction ofinnateandacquired immunity(6min)(5)Theorgans,tissuesandcells'in innateimmunesystem(7min)(6)Leukocytesfunctions and mechanism in innate immunity(8min)Lecture.2:
苏州大学医学部药学院授课教案 授课教师：王媛授课日期：2021年3月19日 课程名称 Microbiology and immunology（英文） 所属学科 药学 教材名称 Foundations in Microbiology 10th Edition Kuby Immunology 7th Edition 授课年级 药学全英班 二年级 授课章节 Innate immunity 授课时间 150分钟 一、教学目标：含知识目标、技能（能力）目标 1. 知识目标： (1) To understand the principles of host defense and immune responses (2) To understand the process and functions of innate immunity (inflammation, phagocytosis, interferons) (3) To understand and grasp the function and mechanism of complement system 2. 技能（能力）目标：结合实验课程目标 二、授课内容（依据教学大纲）及时间分配 Lecture 1: (1) The characteristics of basic host defenses (5 min) (2) Introduction of three lines of host defense (5 min) (3) First line of host defense: different barriers’ components, structure and functions (4 min) (4) Introduction of innate and acquired immunity (6 min) (5) The organs, tissues and cells’ in innate immune system (7 min) (6) Leukocytes’ functions and mechanism in innate immunity (8 min) Lecture 2:
(7) The Inflammatory Response and its features(4min)(8)Theprocessand stagesof Inflammation(10min)(9)InflammatoryMediators,theirfunctions and mechanisms(55min)(io)Phagocytosis:Phagocytes, Phases(8min)(ll) Interferon: Types, roles and mechanisms(8min)Lecture3(12)Complement introduction: components,terms,and features(15min)(13) Complement activation pathways(10 min)(14)Classic pathway(5min)(15) MB-lectin pathway(5 min)(16)alternative pathways(10min)(17)Complement functions:Cytosis,Opsonization,Immune complex clearance, Inflammatory mediators,Involvement inacquired immune responses(20min)(155/min)(18) Complement activation regulation三教学重点与难点教学重点1.(1) 3 activation pathways of complement system
(7) The Inflammatory Response and its features (4 min) (8) The process and stages of Inflammation (10 min) (9) Inflammatory Mediators, their functions and mechanisms (5 min) (10) Phagocytosis: Phagocytes, Phases (8 min) (11) Interferon: Types, roles and mechanisms (8 min) Lecture 3 (12) Complement introduction: components, terms, and features (15 min) (13) Complement activation pathways (10 min) (14) Classic pathway(5 min) (15) MB-lectin pathway(5 min) (16) alternative pathways (10 min) (17) Complement functions: Cytosis, Opsonization, Immune complex clearance, Inflammatory mediators, Involvement in acquired immune responses (20 min) (18) Complement activation regulation (15 min) 三、教学重点与难点 1. 教学重点 (1) 3 activation pathways of complement system
(2)Functionsof complement system2.教学难点(i) The procedures of complement activation(2)Theregulation mechanisms of complement activation四、教学方法选择1.理论课堂教学A.多媒体教学：（简要列出本章节多媒体教学设计特点及优势）(i)Examples andexplanation of.certain inflammations(2)Introduce the story how the complement system was found and investigated by scientist to heighten the curiosity andinterest of studentsB.互动教学：（根据实际情况列出案例/实例讨论、分析讨论、分组讨论、翻转课堂等互动教学内容标题）(i) Draw the schematic diagram with students to better understand the cascade of complement activation(2)Discuss thecomplicatedknowledgepoints(3) Solve problems together with students2.实验教学：（简要列出实验内容标题）Notapplicable福
(2) Functions of complement system 2. 教学难点 (1) The procedures of complement activation (2) The regulation mechanisms of complement activation 四、教学方法选择 1. 理论课堂教学 A.多媒体教学：（简要列出本章节多媒体教学设计特点及优势） (1) Examples and explanation of certain inflammations (2) Introduce the story how the complement system was found and investigated by scientist to heighten the curiosity and interest of students B.互动教学：（根据实际情况列出案例/实例讨论、分析讨论、分组讨论、翻转课堂等互动教学内容标题） (1) Draw the schematic diagram with students to better understand the cascade of complement activation (2) Discuss the complicated knowledge points (3) Solve problems together with students 2. 实验教学：（简要列出实验内容标题） Not applicable
五、更新或补充内容提要六复习思考题(1)What is the difference between innate and acquired immunity? What are the general characteristics of each?(2)Howdoes the immune system distinguish self fromforeign cells and particles?(3)What is the cascade in the 3 complement activation pathways?(4)What are the basic functions of complement system?(5) How the complement activation is regulated?七、学习资源、课外自主学习参考图文并茂的科学综述期刊：NatureReviewsImmunology苏州大学医学部药学院授课教案授课教师：郑毅然授课日期：2021年3月24日药学课程名称所属学科Microbiologyandimmunology(英文)药学全英班Foundations in Microbiology lOth Edition教材名称授课年级Kuby Immunology 7th Edition二年级授课章节Adaptiveimmunity:Antigen,MHC andAntibody授课时间150分钟教学目标：含知识目标、技能（能力）目标71.知识目标：
五、更新或补充内容提要 六、复习思考题 (1) What is the difference between innate and acquired immunity? What are the general characteristics of each? (2) How does the immune system distinguish self from foreign cells and particles? (3) What is the cascade in the 3 complement activation pathways? (4) What are the basic functions of complement system? (5) How the complement activation is regulated? 七、学习资源、课外自主学习参考 图文并茂的科学综述期刊：Nature Reviews Immunology 苏州大学医学部药学院授课教案 授课教师：郑毅然授课日期：2021年3月24日 课程名称 Microbiology and immunology（英文） 所属学科 药学 教材名称 Foundations in Microbiology 10th Edition Kuby Immunology 7th Edition 授课年级 药学全英班 二年级 授课章节 Adaptive immunity: Antigen, MHC and Antibody 授课时间 150分钟 一、教学目标：含知识目标、技能（能力）目标 1.知识目标：
(1) Know the similarities and differences between innate and adaptive immune system(2) Grasp the definition of antigens, factors contributing to antigenicity, the different types of antigens and theirrespective function(3)Know the structure and function of MHC molecules(4)Understand the origin of diversity for MHC molecules and the biological significance for such diversity(5)Know the endogenous and exogenous antigen presentation pathways and understand the different function the twoantigen presentation pathways(6)Know the structure of antibodies, main classes of antibodies and their characteristic structure and function2.技能（能力）目标：(1) Learn the basic immunology terms in English(2)Improvethe:reading,and writingofscientificEnglishlistening,speaking二、授课内容（依据教学大纲））及时间分配Lecture 1:(1) Compare and contrast the innate andadaptive immune system (1o min)(2)Definitions of antigen,antigenicity (lo min)(3)The origin of antigens (5 min)(4)Factors affecting antigenicity and their applications in inducing immune response (13 min)(5)Thestructureandfunction of differenttypesof antigens (12min)Lecture2:(6)Structureand functionof MHC ClassIand Class IImolecules(15min)(7)Expression pattern of MHCmolecules(10 min)(8)Theorigin of diversityof MHCmolecules (15min)(9) Antigenpresenting cells (10min)
(1) Know the similarities and differences between innate and adaptive immune system (2) Grasp the definition of antigens, factors contributing to antigenicity, the different types of antigens and their respective function (3) Know the structure and function of MHC molecules (4) Understand the origin of diversity for MHC molecules and the biological significance for such diversity (5) Know the endogenous and exogenous antigen presentation pathways and understand the different function the two antigen presentation pathways (6) Know the structure of antibodies, main classes of antibodies and their characteristic structure and function 2.技能（能力）目标： (1) Learn the basic immunology terms in English (2) Improve the reading, listening, speaking and writing of scientific English 二、授课内容（依据教学大纲）及时间分配 Lecture 1: (1) Compare and contrast the innate and adaptive immune system (10 min) (2) Definitions of antigen, antigenicity (10 min) (3) The origin of antigens (5 min) (4) Factors affecting antigenicity and their applications in inducing immune response (13 min) (5) The structure and function of different types of antigens (12 min) Lecture 2: (6) Structure and function of MHC Class I and Class II molecules (15 min) (7) Expression pattern of MHC molecules (10 min) (8) The origin of diversity of MHC molecules (15 min) (9) Antigen presenting cells (10 min)