Normal bases Modified bases 7.3 tRNA contains modified bases that 真”0 influence its pairing Uridine s ibothymidine(D) Dihydrour idine( D)Pseudour id ine()4-thiou dine(S uI properties gure 7.6 All of Cytidine 3-methylcytidine 5-methylcytidine the four bases in tRNa can be Adenos ine modified CH o 消当 Guanosine 7-methylguanosine Queuosine(Q) cosine ( Y
Figure 7.6 All of the four bases in tRNA can be modified. 7.3 tRNA contains modified bases that influence its pairing properties
H 7.3 tRNA contains H H modified bases that influence its pairing Sugar properties Cytosine nosine Sug Figure 7.7 Modification to Sugar aH inosine allows Uracil N pairing with U, C Inosine Sugar and a H 消当 Sugar Adenine Inosine Sugar
Figure 7.7 Modification to inosine allows pairing with U, C, and A. 7.3 tRNA contains modified bases that influence its pairing properties
One bond is not enough 7.3 tRNA contains modified bases that H influence its pairing properties Sugar H Thiouracil h N N Guanine Sugar Figure 7. 8 2-thiouracil pairs only w ith A Modification to 2 CH3 thiouridine restricts pairing to a alone because only one H- ond can form with g Sugar H Thiouracil H Adenine 消当 Sugar
Figure 7.8 Modification to 2- thiouridine restricts pairing to A alone because only one Hbond can form with G. 7.3 tRNA contains modified bases that influence its pairing properties