Chapter 7 Using the genetic code 莘大
Chapter 7 Using the genetic code
7. 1 Introduction 7.2 Codon-anticodon recognition involves wobbling 7. 3 tRNA contains modified bases that influence its pairing properties 7. There are sporadic alterations of the universal code) 7.5 tRNAS are charged with amino acids by synthetases 7.6 Accuracy depends on proofreading 7.7 Suppressor tRNAs have mutated anticodons that read new codons 7. 8 The accuracy of translation 7.9 tRNA may influence the reading frame 消当
7.1 Introduction 7.2 Codon-anticodon recognition involves wobbling 7.3 tRNA contains modified bases that influence its pairing properties 7.4 (There are sporadic alterations of the universal code) 7.5 tRNAs are charged with amino acids by synthetases 7.6 Accuracy depends on proofreading 7.7 Suppressor tRNAs have mutated anticodons that read new codons 7.8 The accuracy of translation 7.9 tRNA may influence the reading frame
7.1 Introduction Stop codons are the three triplets qUAA, UAg UGA) which terminate protein synth hesis 消当
Stop codons are the three triplets (UAA, UAG, UGA) which terminate protein synthesis. 7.1 Introduction
7.1Introduction U Leu/ UcaS se, UAg y/UGU Phe UCl UAU UCC UGC UAA STOP ∪ GA STOP UCG UGe Tr Figure 7. 1 All the CG triplet codons have CUC LeU cCA CCCl P CAULHIS CGCLArg CAC CUA CAA GIn CG meaning: 61 CUG cCG CAG CGG represent amino AUA ACA// AACrAsn Ser A ACI AAU AUC\ le ACC GC acids. and 3 cause AUG Met ACGAAC AA凡 ys AGGI9 termination (STOP) GA GGI GUC GGC GUA GG G Glu GGG 消当
Figure 7.1 All the triplet codons have meaning: 61 represent amino acids, and 3 cause termination (STOP). 7.1 Introduction
7.1Introduction Per cent of residues in protein 10 eur 8 Ala Glu y ser● Figure 7.2 The 6 Lys● Val le● h AS number of codons Pro: Arg● A for each amino acid Pheb does not correlate Met. His● closely with its Tm frequency of use in 4 5 proteins Number of codons 消当
Figure 7.2 The number of codons for each amino acid does not correlate closely with its frequency of use in proteins. 7.1 Introduction