Bowman's space BS Pedicles of podocytes Basement Fenestrated endothelial lining Capillary lumen
Bowman’s space Capillary lumen Fenestrated endothelial lining Basement membrane Pedicles of podocytes
Urine Bowman’ s capsu|e GFR=125 ml/min (Alb=4 mg/L Podocytes GBM Endothelium ESL Endothelia Blood Surface Layer Capillary loop Qn=700 ml/min [Ab]=40g/
Bowman’s capsule Capillary loop Endothelial Surface Layer
Glomerular disease Damage of filtration barrier Inflammation Accumulation of white blood cells Deposition of immune active substance Leakage of plasma proteins and blood cells a Hematuria Proteinuria
Glomerular disease Damage of filtration barrier Inflammation Accumulation of white blood cells Deposition of immune active substance Leakage of plasma proteins and blood cells Hematuria Proteinuria
Approach to the patient with glomerular disease Hematuria Proteinuria Pyuria Renal insuficiency /renal failure
Approach to the patient with glomerular disease Hematuria Proteinuria Pyuria Renal insuficiency / renal failure
Hematuria Microscopic hematuria Asymptomatic Accompanied by proteinuria Red cell casts or dysmorphic red blood cells Gross hematuria Benign prostatic hypertrophy, interstitial nephritis, papillary necrosis, renal stones cystic kidney diseases, renal vascular injury
Hematuria Microscopic hematuria Asymptomatic Accompanied by proteinuria Red cell casts or dysmorphic red blood cells Gross hematuria Benign prostatic hypertrophy, interstitial nephritis, papillary necrosis, renal stones, cystic kidney diseases, renal vascular injury