b.Pharmacodynamics of Benzodiazepines Barbiturates i.Molecular Pharmacology of the GABAA Receptor ii.Neuropharmacology iii.Organ Level Effects .Tolerance:PsychologiPhysiologic Dependence iv.BENZODIAZEPINE ANTAGONISTS :FLUMAZENIL v.NEWER DRUGS FOR ANXIETY SLEEF DISORDERS Vi.CLINICAL PHARMACOLOGY OF SEDATIVE- HYPNOTICS TREATMENT OF ANXIETY STATES vii.TREATMENT OF SLEEP PROBLEMS Pharmacologic Management of Parkinsonism and Other Movement Disorders Total hours required= Total Classes required= 2 Days of Study Mon,Tue,Wed,Thu,Fri,Mon,Tue, Wed Test= Thursday Period of Study Week 1&2-First semester a.Lecture 1 Class XVIIl i.Etiology of Parkinsonism ii.Therapy method of Parkinsonism a.Increases brain dopamine levels levodopa b.Dopamine agonists,directly stimulate DA receptors c.Monoamine oxidase (MAO)inhibitors,prevent dopamine metabolism d.Anticholinergic agents iii.Pharmacokinetics of levodopa Iv.Clinical Use v.Adv se Effect b.Lecture 2 Class XIX i.Drug Interactions c.In patients with glaucoma d.Antipsychotic drug ii.Contraindications
b. Pharmacodynamics of Benzodiazepines & Barbiturates i. Molecular Pharmacology of the GABAA Receptor ii. Neuropharmacology iii. Organ Level Effects c. Tolerance: Psychologic & Physiologic Dependence iv. BENZODIAZEPINE ANTAGONISTS: FLUMAZENIL v. NEWER DRUGS FOR ANXIETY & SLEEP DISORDERS vi. CLINICAL PHARMACOLOGY OF SEDATIVEHYPNOTICS TREATMENT OF ANXIETY STATES vii. TREATMENT OF SLEEP PROBLEMS Pharmacologic Management of Parkinsonism and Other Movement Disorders Total hours required = 4 Total Classes required = 2 Days of Study = Mon, Tue, Wed, Thu, Fri, Mon, Tue, Wed Test= Thursday Period of Study = Week 1&2 –First semester a. Lecture 1 Class XVIII i. Etiology of Parkinsonism ii. Therapy method of Parkinsonism a. Increases brain dopamine levels levodopa b. Dopamine agonists, directly stimulate DA receptors c. Monoamine oxidase (MAO) inhibitors, prevent dopamine metabolism d. Anticholinergic agents iii. Pharmacokinetics of levodopa iv. Clinical Use v. Adverse Effect b. Lecture 2 Class XIX i. Drug Interactions a.Vitamin pyridoxine(B6) b. MAO inhibitors (phenelzine) c. In patients with glaucoma d. Antipsychotic drug ii. Contraindications
iii.Specific agents a.Dopamine Agonists:Bromocriptine b.Monoamine oxidase inhibitors:rasagiline c.Catechol-O-Methyl Transferase Inhibit ors :tolcapone and entacapone d.Anticholinergic Drugs opioid analgesics and antagonist opioid analgesics and antagonist Total hours required Total Classes required Days of Study Mon,Tue,Wed.Thu,Fri,Mon,Tue Wed Test= Thursday Period ofStudy Week 1&2-First semester Lecture 1 Class XX i.The classification of the pain ii.Classification of the opioid analgesics iii.Mechanism ofaction iv.Tolerance and Physical Dependence v.Organ system effects of morp he and its surrogates a.Central nervous system effects b.Peripheral effects vi.Clinical use of opioid analgesics vii.Toxicity and adverse reaction of opioid analgesics viii.Diagnosis and treatment of opioid overdosage ix.Contraindication and cautions in therapy a.Use of pure agonists with weak partial agonists b.Use in patients with head injuries c.Use during pregnancy d.Use in patients with impaired pulmonary function e.Use in patients with impaired hepatic or renal Function f.Use in patients with endocrine disease x.Specific agents,Meperidine xi.The opiod antagonist Antipsychotic Drugs Total hours required= Total Classes required= 2
iii. Specific agents a. Dopamine Agonists : Bromocriptine b. Monoamine oxidase inhibitors: rasagiline c. Catechol-O-Methyl Transferase Inhibitors :tolcapone and entacapone d. Anticholinergic Drugs opioid analgesics and antagonist opioid analgesics and antagonist Total hours required = 2 Total Classes required = 1 Days of Study = Mon, Tue, Wed, Thu, Fri, Mon, Tue, Wed Test= Thursday Period of Study = Week 1&2 –First semester Lecture 1 Class XX i. The classification of the pain ii. Classification of the opioid analgesics iii. Mechanism of action iv. Tolerance and Physical Dependence v. Organ system effects of morphine and its surrogates a. Central nervous system effects b. Peripheral effects vi. Clinical use of opioid analgesics vii.Toxicity and adverse reaction of opioid analgesics viii. Diagnosis and treatment of opioid overdosage ix. Contraindication and cautions in therapy a. Use of pure agonists with weak partial agonists b. Use in patients with head injuries c. Use during pregnancy d. Use in patients with impaired pulmonary function e. Use in patients with impaired hepatic or renal Function f. Use in patients with endocrine disease x. Specific agents, Meperidine xi. The opiod antagonist Antipsychotic Drugs Total hours required = 4 Total Classes required = 2