25.3 Coated vesicles transport both exported and imported proteins Coated vesicles are vesicles whose membrane has on its surface a layer of a protein such as clathrin, cop-I or COP-II Endocytosis is process by which proteins at the surface of the cell are internalized, being transported into the cell within membranous vesicles Exocytosis is the process of secreting proteins from a cell into the medium, by transport in membranous vesicles from the endoplasmic reticulum, through the Golgi, to storage vesicles, and finally(upon a regulatory signal) through the plasma membrane Retrograde transport describes movement of proteins in the reverse direction in the reticuloendothelial system, typically from Golgi to endoplasmic reticulum 消当
Coated vesicles are vesicles whose membrane has on its surface a layer of a protein such as clathrin, cop-I or COP-II. Endocytosis is process by which proteins at the surface of the cell are internalized, being transported into the cell within membranous vesicles. Exocytosis is the process of secreting proteins from a cell into the medium, by transport in membranous vesicles from the endoplasmic reticulum, through the Golgi, to storage vesicles, and finally (upon a regulatory signal) through the plasma membrane. Retrograde transport describes movement of proteins in the reverse direction in the reticuloendothelial system, typically from Golgi to endoplasmic reticulum. 25.3 Coated vesicles transport both exported and imported proteins
25.3 Coated vesicles transport both exported and imported proteins 到 Plasma membrane Vesicle fuses External forms with mern brane Unknown vesicles secretory 0R把 COP-E-yesicle cis face Endosome es icle AN pinches oft. t Endoplasmic Reticulum Figure 25.8 Proteins are transported in coated vesicles. Constitutive(bulk flow) transport from ER through the golgi takes place by COP-coated vesicles Clathrin-coated vesicles are used for both regulated exocytosis and endocytosis 消当
Figure 25.8 Proteins are transported in coated vesicles. Constitutive (bulk flow) transport from ER through the Golgi takes place by COP-coated vesicles. Clathrin-coated vesicles are used for both regulated exocytosis and endocytosis. 25.3 Coated vesicles transport both exported and imported proteins
25.3 Coated vesicles transport both exported and imported proteins Clathnin-coated vesicle Figure 25.9 Coated vesicles are released from the trans face of trans Golgi the golgi. The diameter of a vesicle is 70 nm Photograph kindly Cis Golg provided by Lelio orci Nonclathrin-coated vesicle 消当
Figure 25.9 Coated vesicles are released from the trans face of the Golgi. The diameter of a vesicle is ~70 nm. Photograph kindly provided by Lelio Orci. 25.3 Coated vesicles transport both exported and imported proteins
25.3 Coated vesicles transport both exported and imported proteins Veside release icle fusion Figure 25.2 Vesicles are CYTOSOL CYTOSOl O 'esicle cont act released when they bud from target membrane a donor compartment and are 你e surrounded by coat proteins (left). During fusion, th Coat is rem oved coated vesicle binds to a Veside buds from mem brane target compartment, Is uncoated and fuses with the target mem brane target membrane. releasing g its contents (right) Veside is released 消当
Figure 25.2 Vesicles are released when they bud from a donor compartment and are surrounded by coat proteins (left). During fusion, the coated vesicle binds to a target compartment, is uncoated, and fuses with the target membrane, releasing its contents (right). 25.3 Coated vesicles transport both exported and imported proteins
Cytosol 25.3 Coated vesicles transport both exported Coat proteins and imported proteins membrane membrane Figure 25.10 Vesicle formation results when coat Proteins surround embrane proteins bind to a membrane extrusion deform it, and ultimately surround a membrane vesicle Coated vesicle that is pinched off. pinches off 消当
Figure 25.10 Vesicle formation results when coat proteins bind to a membrane, deform it, and ultimately surround a membrane vesicle that is pinched off. 25.3 Coated vesicles transport both exported and imported proteins