24.4 The diversity of germline information 36V 40w 1-5 Figure 24.9 The human and mouse kappa families consist of V gene segments linked to 5 J segments connected to a single C gene segment 清菜大当
Figure 24.9 The human and mouse kappa families consist of V gene segments linked to 5 J segments connected to a single C gene segment. 24.4 The diversity of germline information
24.4 The diversity of germline information VH genes D segments J C gene segm ents w300 m20 6μδ I01Il 1n fi 月1AY 的 kh300 250 200 150 100 50 Figure 24.10 A single gene cluster in man contains all the information for heavy-chain gene assembly. 清菜大当
Figure 24.10 A single gene cluster in man contains all the information for heavy-chain gene assembly. 24.4 The diversity of germline information
24.4 The diversity of germline information Figure 24.11 25 Vpseudogenes V1 J The chicken DDDD月●0D0●gD0●DD自D00B0DD0D lambda light ■ locus has 25 V V-J joining. pseudogenes upstream of the single functional V-J-C region. ◆ . But sequences 角■■■■■■■■■■■■■■海 derived from the P seudogene sequence replaces corresponding part of V,1 pseudogenes are found in active rearranged V-J- C genes. 清第大当
Figure 24.11 The chicken lambda light locus has 25 V pseudogenes upstream of the single functional V-J-C region. But sequences derived from the pseudogenes are found in active rearranged V-JC genes. 24.4 The diversity of germline information