HISTORY OF PATHOGENIC E.COLI ×大多数存在于动物胃肠道的E.coli不致病 可能在肠中对合成维生素K起作用 ×Shiga toxin基因水平转移到E.coli ×致病性E.coli慢慢分化成多个血清型
大多数存在于动物胃肠道的E. coli不致病 可能在肠中对合成维生素K起作用 Shiga toxin基因水平转移到E. coli 致病性E. coli 慢慢分化成多个血清型
aggregative adherence mucus biofilm intimate attachment of bacteria actin Delivery of cytotoxin condensation and microvillous Delivery of LT or ST effacement enterotoxins delivery of shiga toxin ETEC EHEC EAEC elongated initial adherence via BFP intimate attachment normal cytoplasm invasion actin condensation phagosomal and microvillous rupture effacement lateral intracellular spread to movement adjacent cell DAEC EPEC EIEC
ESCHERICHIA CQLI Q157:H7 G,不形成芽孢，棒杆 菌 兼性厌氧 ×Temp10-50°C(opt30 37°C). ×Min aw0.93 × 低pH,低温下存活
G-，不形成芽孢，棒杆 菌 兼性厌氧 Temp 10-50˚C (opt 30- 37˚C). Min aW 0.93 低pH，低温下存活
×E.coi0157:H7近些年才出现 ×第一例：1984 Where has it been all this time?
E. coli O157:H7 近些年才出现 第一例：1984 Where has it been all this time?