CHAPTER 7.HAZARD CHARACTERIZATION 危害特征描述
COMPONENTS OF RISK ASSESSMENT Hazard Identification Dose-Response Assessment Exposure Assessment Risk Characterization
Hazard Identification Dose-Response Assessment Exposure Assessment Risk Characterization
DEFINITION The qualitative and/or quantitative evaluation of the nature of the adverse health effects associated with biological,chemical and physical agents which may be present in food.For chemical agents,a dose-response assessment should be performed.For biological or physical agents,a dose-response assessment should be performed if the data are obtainable. +有害作用属性的定性或定量评价 +化学危害的剂量-反应评估 +微生物或物理危害有条件下的的剂量-反应评估
The qualitative and/or quantitative evaluation of the nature of the adverse health effects associated with biological, chemical and physical agents which may be present in food. For chemical agents, a dose-response assessment should be performed. For biological or physical agents, a dose-response assessment should be performed if the data are obtainable. 有害作用属性的定性或定量评价 化学危害的剂量-反应评估 微生物或物理危害有条件下的的剂量-反应评估
DOSE-RESPONSE x"All substances are poisons;there is none which is not a poison.The right dose differentiates a poison from a remedy." Paracelsus (1493-1541)
“All substances are poisons; there is none which is not a poison. The right dose differentiates a poison from a remedy.” Paracelsus (1493-1541)
KEY WORDS Dose Response Risk Hazard X Exposure Individual Sensitivity
Risk = Hazard X Exposure Dose / Response Individual Sensitivity