26.1Introduction Figure 26.2 Three means for transferring material of various sizes into the cell are provided by ion channels. receptor mediated ligand lors ente Lig and s through ch anne released transport and receptor internalization Coated vesicle 消当 ndo closed
Figure 26.2 Three means for transferring material of various sizes into the cell are provided by ion channels, receptormediated ligand transport, and receptor internalization. 26.1 Introduction
26.1Introduction Figure 26. 3A signal may wwii be transduced by Target activating the kinase Target activity of the ↓ cytoplasmic domain of a transmembrane receptor or by dissociating a g P. PY protein into subunits that Target act on target proteins on Phosphory lated receptor G protein dissociates the membrane associates with tar get protein activ e subunit(s) act on target 消当
Figure 26.3 A signal may be transduced by activating the kinase activity of the cytoplasmic domain of a transmembrane receptor or by dissociating a G protein into subunits that act on target proteins on the membrane. 26.1 Introduction
Carrier Channel 26.2 Carriers and channels EXTRACELLULAR olute binds Gate is form water soluble paths to carrier through the membrane w暖日k CYTOSOL Figure 26.4 A carrier(porter) transports a solute into the cell by ↓ a conformational change that EX TRACELLULAR brings the solute-binding site from the exterior to the interior while an ion channel is controlled by the opening of a gate(which might in principle be located on either side Solute expo se d/gate opens: ions/23 of the membrane) to cytoso travel through CYTOSOL 消当
Figure 26.4 A carrier (porter) transports a solute into the cell by a conformational change that brings the solute-binding site from the exterior to the interior, while an ion channel is controlled by the opening of a gate (which might in principle be located on either side of the membrane). 26.2 Carriers and channels form water soluble paths through the membrane
Carrier Channel 26.2 Carriers and channels EXTRACELLULAR olute binds Gate is form water soluble paths to carrier through the membrane w暖日k CYTOSOL Figure 26.4 A carrier(porter) transports a solute into the cell by ↓ a conformational change that EX TRACELLULAR brings the solute-binding site from the exterior to the interior while an ion channel is controlled by the opening of a gate(which might in principle be located on either side Solute expo se d/gate opens: ions/23 of the membrane) to cytoso travel through CYTOSOL 消当
Figure 26.4 A carrier (porter) transports a solute into the cell by a conformational change that brings the solute-binding site from the exterior to the interior, while an ion channel is controlled by the opening of a gate (which might in principle be located on either side of the membrane). 26.2 Carriers and channels form water soluble paths through the membrane
26.2 Carriers and channels form water soluble paths through the membrane Charged face of heliⅸ Hydrophobic face of helⅸ Figure 26.5 A channel may be created by amphipathic helices, which present their hydrophobic faces to the lipid bilayer, while juxtaposing their charged faces away from the bilayer. In this example, the channel is lined with positive charges, which would encourage the passage of anions 消当
Figure 26.5 A channel may be created by amphipathic helices, which present their hydrophobic faces to the lipid bilayer, while juxtaposing their charged faces away from the bilayer. In this example, the channel is lined with positive charges, which would encourage the passage of anions. 26.2 Carriers and channels form water soluble paths through the membrane