Adherence Adhesions/ligands bind to receptors on host cells ·Glycocalyx Streptococcus mutans 。Fimbriae Escherichia coli 。M protein Streptococcus pyogenes 。Opa protein Neisseria gonorrhoeae 。Tapered end Treponema pallidum
• Adhesions/ligands bind to receptors on host cells • Glycocalyx Streptococcus mutans • Fimbriae Escherichia coli • M protein Streptococcus pyogenes • Opa protein Neisseria gonorrhoeae • Tapered end Treponema pallidum Adherence
Enzymes 。Coagulase Coagulate blood 。Kinases Digest fibrin clots 。Hyaluronidase Hydrolyses hyaluronic acid 。Collagenase Hydrolyzes collagen ·IgA proteases Destroy IgA antibodies ·Siderophores Take iron from host iron- binding proteins 。Antigenic variation Alter surface proteins
• Coagulase Coagulate blood • Kinases Digest fibrin clots • Hyaluronidase Hydrolyses hyaluronic acid • Collagenase Hydrolyzes collagen • IgA proteases Destroy IgA antibodies • Siderophores Take iron from host ironbinding proteins • Antigenic variation Alter surface proteins Enzymes
Penetration into the Host Cell Figure 15.2
Penetration into the Host Cell Figure 15.2
Toxins 。Toxin Substances that contribute to pathogenicity 。Toxigenicity Ability to produce a toxin Toxemia Presence of toxin the host's blood 。Toxoid Inactivated toxin used in a vaccine 。 Antitoxin Antibodies against a specific toxin
Toxins • Toxin Substances that contribute to pathogenicity • Toxigenicity Ability to produce a toxin • Toxemia Presence of toxin the host's blood • Toxoid Inactivated toxin used in a vaccine • Antitoxin Antibodies against a specific toxin