The tissue triad in skin and nerves Nerve Skin Axon epidermIs basement membrane Basement membrane. o Myelin sheath Endoneurium dermis 99 epineurium
The tissue triad in skin and nerves
The tissue triad in the organism BM is thick, solid line ski cardiovascular and mesothelial spaces fat cells Supporting tissues (stroma) nervous and endocrine systems genItourInary respiratory gastrointestinal exocrine systems skeletal smooth muscle fibers heart
The tissue triad in the organism BM is thick, solid line
Problems and advantages of chemical symbolism No stoichiometric data currently available! How many cells? What is concentration of cytokine X? Ligand density ?"Reaction diagrams", not chemical equations Neither reactants nor products currently have standardized time-invariant structure, as do chemical compounds. BUT gain rapid estimate of minimum requirements for synthesis of tissues and organs. Look for similarities between different organs (e.g, skin VS. nerves)
Problems and advantages of chemical symbolism • No stoichiometric data currently available! How many cells? What is concentration of cytokine X? Ligand density? “Reaction diagrams”, not chemical equations. • Neither reactants nor products currently have standardized, time-invariant structure, as do chemical compounds. • BUT gain rapid estimate of minimum requirements for synthesis of tissues and organs. • Look for similarities between different organs (e.g., skin vs. nerves)