Severity of HIE in Full-term Neonate Mild Moderate severe consciousness Hyperalertness Lethargy Coma Seizure Jitteriness Variable Primitive reflexes Exaggerated Suppressed Absent Muscle tone Hypertonia Weakness Floppy normal Brain stem
Severity of HIE in Full-term Neonate Mild Moderate severe consciousness Hyperalertness Lethargy Coma Seizure -, Jitteriness Variable + Primitive reflexes Exaggerated Suppressed Absent Muscle tone Hypertonia Weakness Floppy Normal Brain stem _ _ +
Diagnosis 1, History of hypoxia or ischemia 2、 Clinical features 3、 Neuroimaging Electrodiagnostic techniques 5, Neuronal biochemistry
Diagnosis 1、History of hypoxia or ischemia 2、Clinical features 3、Neuroimaging 4、Electrodiagnostic techniques 5、Neuronal biochemistry
Neuroimaging(神经影像) 1、 Cranial Ultrasound(头颅超声) (1)Diffuse increased echogenicity of parenchyma (2) Effacement of cortical sulci (3) Increased periventricular echoes
Neuroimaging（神经影像） 1、Cranial Ultrasound (头颅超声) （1）Diffuse increased echogenicity of parenchyma （2）Effacement of cortical sulci （3）Increased periventricular echoes
Neuroimaging 2 Computed Tomography (CT) (1) Focal or generalized low tissue attenuation(低密度) (2) Focal or generalized cerebral atrophy (3) Multicystic encephalomalacia(多囊脑软化) (4)Limited value for early assessment in preterm neonate
Neuroimaging 2、Computed Tomography (CT) （1）Focal or generalized low tissue attenuation (低密度) （2）Focal or generalized cerebral atrophy （3）Multicystic encephalomelacia (多囊脑软化) （4）Limited value for early assessment in preterm neonate
脑萎缩和脑软化
脑萎缩和脑软化