WhatisPeroaied Medie7
What is
"One sizefits all"modelPersonalizedmedicineAnextension oftraditionalmedicineAfocus ongeneticmap andproteomics“"Personal"treatment
Personalized Medicine ❖ An extension of traditional medicine ❖ A focus on genetic map and proteomics ❖ “Personal” treatment “One size fits all” model Personalized medicine
Personalized MedicineGo withTumor
Personalized Medicine Go with Tumor
InfommedPatients with retractoryconsentcancer (all tumortypes)slgnedTumorblopsyNGS+Cytogcan HDHHCTherapybasedon molecular proflingApproved.moleculanytargetedagentIntormedRBioinformaticsconsentsignedConventional therapybasedononcologlst's cholceMoleculerNon ellglbieEllgiblebloiogypetientpatlentboardCros9-0verSpectricYESNOtherapy0avallableinstitutCurie
Disease-causingmutationtest--to prevent cancers表1BRCAI与BRCA2在乳腺腺病组织及乳腺癌中的表达BRCA1BRCA2例数组别阴性阳性阴性阳性13533432乳腺腺病2690642466乳腺瘤BRCA1 andBRCA2BRCA2encodes3814aminoacidpolypeptideTransactivationRad51BRCrepeatsdomain国Cancerprevention
Applications ❖Disease-causing mutation test -to prevent cancers Cancer prevention