Lecture 2 Antigen Zhijian Cai, Ph. D Institute of immunology ZJU
Antigen Zhijian Cai, Ph.D Institute of immunology, ZJU Lecture 2
1. Introduction 2. Antigenicity and specificit 3. Requirements for immunogenicity 4. Types of antigens 5. Superantigen immunological adjuvants and mItogen
1. Introduction 2. Antigenicity and specificity 3. Requirements for immunogenicity 4. Types of antigens 5. Superantigen ,immunological adjuvants and mitogen
Introduction 1.Antigen(Ag)-a substance that induces a specific immune response and can specifically bind to antibodies and effect t and b cells Alternative name-lmmunogen 2. Property of Ag- immunogenicity and antigenicity Complete Ag has immunogenicity and antigenicity
Introduction 1.Antigen (Ag) – A substance that induces a specific immune response and can specifically bind to antibodies and effect T and B cells. Alternative name - Immunogen 2.Property of Ag - immunogenicity and antigenicity Complete Ag has immunogenicity and antigenicity
Introduction 3. Hapten -a substance that is non- immunogenic but which can react with the products of a specific immune response. Haptens are small molecules which could never induce an immune response when administered by themselves but which can when coupled to a carrier molecule Haptens have the property of antigenicity but not immunogenicity 4. Tolerogen, allergen
Introduction 3.Hapten - A substance that is non-immunogenic but which can react with the products of a specific immune response. Haptens are small molecules which could never induce an immune response when administered by themselves but which can when coupled to a carrier molecule. Haptens have the property of antigenicity but not immunogenicity. 4. Tolerogen,allergen
Antigenicity and specificity Antigenicity The ability of a compound to bind with antibodies or with cells of the immune system This binding is highly specific
Antigenicity and specificity * Antigenicity The ability of a compound to bind with antibodies or with cells of the immune system. This binding is highly specific