Testing and ThinkingImmotile cilia syndrome patients havedefective不动纤毛综合征A.myosin B.tubulin C. dynein D.actinWhat mechanism is responsible formovements of cilia and flagella?A.Kinesin moving on microfilamentsB.Dynein moving on microfilamentsC. Dynein moving on microtubulesD.Myosin moving on microfilaments生1926
1 不动纤毛综合征 Immotile cilia syndrome patients have defective _. A. myosin B. tubulin C. dynein D. actin Testing and Thinking What mechanism is responsible for movements of cilia and flagella? A. Kinesin moving on microfilaments B. Dynein moving on microfilaments C. Dynein moving on microtubules D. Myosin moving on microfilaments
extracellularspaceTesting and ThinkingsecretoryvesiclesplasmaOmembraneOUsethediagramofthe celltoguideyou whenGolgiansweringthefollowingquestions.ConsidertransportvesiclesO(cytosol)the cartoondiagram oftheprimaryaminoacid sequenceofa3o0aminoacidreceptorERnucleusshown below:transmembranecytoplasmicsignalingsignal sequence ligandbinding domaindomaindomain个aminoacid#1aminoacid#300a) label the amino-terminus (N-terminus) and the carboxy-terminus (C-terminus)b)Where would thisproteinbelocatedinthe cell?Where would this protein belocatedif the signal sequence were deleted?What domain is inserted into the ER lumen during synthesis of the堂protein?21926
2 Testing and Thinking Use the diagram of the cell to guide you when answering the following questions. Consider the cartoon diagram of the primary amino acid sequence of a 300 amino acid receptor shown below: a) label the amino-terminus (N-terminus) and the carboxy-terminus (C-terminus) b) Where would this protein be located in the cell? c) Where would this protein be located if the signal sequence were deleted? d) What domain is inserted into the ER lumen during synthesis of the protein?
answertransmembranecytoplasmic signalingCOOHNH2signal sequence ligandbindingdomaindomaindomainK1aminoacid#1aminoacid#300b) Where would this protein be located in the cell?plasma membraneWhere would this protein be located if the signasequence were deleted?cytosold)What domain is inserted into the ER lumenduring synthesis oftheprotein?ligand binding domain堂31926
3 answer a) b) Where would this protein be located in the cell? _ plasma membrane c) Where would this protein be located if the signal sequence were deleted? _ cytosol d) What domain is inserted into the ER lumen during synthesis of the protein?_ ligand binding domain
组成纤毛和鞭毛的轴丝axoneme轴丝的微管结构：9+2·外围：质膜包裹·外周：9组双联管，A管与B管·中央：中央鞘包裹一对微管双联管的结构特点·A管：完全微管、内外动力臂放射辐条·B管：不完全微管?1926
4 组成纤毛和鞭毛的轴丝(axoneme) ◆轴丝的微管结构:9+2 ●外围:质膜包裹 ●外周:9组双联管,A管与B管 ●中央:中央鞘包裹一对微管 ◆双联管的结构特点 ●A管:完全微管、内外动力臂、 放射辐条 ●B管:不完全微管
轴丝微管组成与排列特点·9组三联管：基体（basalbody）.9组双联管：近基体?9+2:轴丝·单管：纤毛顶部BasalbodyCiliumRadialOuterCentralCentraldoubletmicrotubulesheathspokeC&81926
5 ◆轴丝微管组成与排列特点 ●9组三联管:基体(basal body) ●9组双联管:近基体 ●9+2:轴丝 ●单管:纤毛顶部