theca lutein ovarian cyst: large amount HCg stimulate internal theca cells (i).symptom (ii). disappearance: within 2-4 month after operation iv gestational vomitting and PIH (i).gestational vomitting ) PIH: when uterus is abnormally enlarged and HCG t v hyperthyroidism (i7% is complicated with slight hyperthyroidism incase:HCG↑↑,T3T4↑↑ vi abdominal pain: generally not severe, often before bleeding occurrence of acute abdomen
iii.theca lutein ovarian cyst:large amount HCG stimulate internal theca cells…… (i).symptom (ii).disappearance:within 2~4 month after operation iv.gestational vomitting and PIH (i).gestational vomitting (ii).PIH:when uterus is abnormally enlarged and HCG↑↑ v.hyperthyroidism: (i)7% is complicated with slight hyperthyroidism (ii)cause:HCG ↑↑, T3T4 ↑↑ vi.abdominal pain:generally not severe,often before bleeding. occurrence of acute abdomen
图12-8手术中的照片。显示双侧黄素囊肿,位于子宫底部的侧面。可见正常输卵管。 (承蒙Dr.J. Donald Woodruff, The Johns Hopkins Hospital, Baltimore,MD提供)
Il. partial hydatidiform mole: may have the major symptoms of complete mole but it is slightly manifested no luteinizing cyst the histologic examination of curettage sample may confirm the diagnosis
II.partial hydatidiform mole:may have the major symptoms of complete mole but it is slightly manifested.no luteinizing cyst .the histologic examination of curettage sample may confirm the diagnosis
Prognosis ] complete mole has the latent risk of local invasion or telemetastasis, research proved that after emptying the mole, the rate of uterine invasion or telemetastasis is 15% and 4% respectively if the patient has the following high-risk factors, the risk of local invasion or telemetastasis may increase 10 times The high-risk factors includes (i).β-HCG>100000UL; (ii). uterine size is obviously larger than that with the same gestational time (iii). the luteinizing cyst is>6cm (iv ). If>40 years old, the risk of invasion and metastasis may be 37%0, If >50 years old, the risk of invasion and metastasis may be 56% (v). repeated mole: the morbidity of invasion and metastasis increase 3.4 times
[Prognosis]: complete mole has the latent risk of local invasion or telemetastasis,research proved that after emptying the mole , the rate of uterine invasion or telemetastasis is 15% and 4% respectively.if the patient has the following high-risk factors,the risk of local invasion or telemetastasis may increase 10 times. The high-risk factors includes: (i).β-HCG>100000IU/L; (ii).uterine size is obviously larger than that with the same gestational time. (iii).the luteinizing cyst is >6cm. (iv). If >40 years old,the risk of invasion and metastasis may be 37%, If >50 years old,the risk of invasion and metastasis may be 56%. (v).repeated mole:the morbidity of invasion and metastasis increase 3~4 times
HCG resolution law It is very important for predicting the prognosis. Normally after emptying the mole, the B-HCG regression curve is steadly decreased, and reach normal level within 9.14 weeks persistent mole if the HCG is still positive 3 months after the mole is completely emptied, called persistent mole
HCG resolution law:It is very important for predicting the prognosis. Normally after emptying the mole, the β-HCG regression curve is steadly decreased,and reach normal level within 9~14 weeks persistent mole: if the HCG is still positive 3 months after the mole is completely emptied,called persistent mole