☆氧化脱氨基 GTP ADP Coo HaN C-H ☆NADP) ↓NADP)H+H ☒ C-0 CH2 +H20 CH2 NH glutamate dehydrogenase CH2 CH2 C00 C00 Glutamate a-Ketoglutarate
☆氧化脱氨基 ☆
☆转氨基作用 C00 coo C=0 COO HaN C-H PLP CH2 C-H CH2 C-0 aminotransferase CH2 R CH2 R COO COO a-Ketoglutarate L-Amino acid L-Glutamate a-Keto acid
☆转氨基作用
NH OH CHs Pyridoxal phosphate (PLP) CH2 H HaN-C NH OH CHs Pyridoxamine phosphate (a) 辅基是VB6成份，磷酸吡多醛和吡多胺的相互转换传递氨基
辅基是VB6成份，磷酸吡多醛和吡多胺的相互转换传递氨基
☆联合脱氨基（谷氨酸脱氢酶） Cellular protein Liver C00 C00 Amino acids from ingested →HN C-H protein R R Amino aeids a-Keto acids C00 C00 C-0 H N-C-H CH2 CH2 CH CHa COO C00 a-Ketoglutarate Glutamste C00 →N H N- -日 C00 C00 Alanine CHz Glutamine from →HN -0 muscle and other tisaue CHa CH Alanine yruvat起 Glutamine (aj NHi.nrea,or uric acid
☆联合脱氨基（谷氨酸脱氢酶）
c-Amino acid a-Ketoglutarate →NADH+NHa H>N NH Urea c-Ketoacid Glutamate NAD*+H2O