Parkinsons disease
11 Parkinson’s Disease
CNS degenerative disease Alzheimer' s disease(AD,阿尔茨海默病) Parkinson' s disease(PD,帕金森病) Huntington disease(HD,亨廷顿病) Amyotrophic lateral sclerosis(ALs 肌萎缩侧索硬化症 12
12 CNS degenerative disease ▪ Alzheimer’s disease (AD,阿尔茨海默病) ▪ Parkinson’s disease (PD,帕金森病) ▪ Huntington disease (HD,亨廷顿病) ▪ Amyotrophic lateral sclerosis (ALS, 肌萎缩侧索硬化症)
Parkinson's Disease Muhammad Ali in alata Olympic Michael J Fox Katharine Hepburn
Muhammad Ali in Alanta Olympic Parkinson’s Disease Michael·J·Fox Katharine Hepburn
Parkinson's Disease- History First described in 1817 by an English physician, James Parkinson, in " An Essay on the Shaking Palsy” “ paralysis agitans”(震颤麻痹) ESSAY SHAKING PALSY CHAPTER I DEFINITION-HISTORY-ILLUSTRATIVE CASES SHAKING PALSY. Paralysis agitans) Involuntarytremulousmotion, withlessened muscular power, in parts not in action and James c. Parkinson even when supported; with a propensity to bend the trunk forwards, and to pass from a walking to a running pace: the senses and intellects being uninjured 14 D三,C
14 ▪ First described in 1817 by an English physician, James Parkinson, in “An Essay on the Shaking Palsy.” ▪ “paralysis agitans” (震颤麻痹) Parkinson’s Disease - History James C. Parkinson
The famous French neurologist, Charcot, further described the syndrome in 1868 ( rigidity)- named” Parkinson disease” 1919:确定病变部位主要在黑质 1960:发现与黑质纹状体中DA含量显著降低有关 每年的4月11日—世界帕金森病日 15
15 ▪ The famous French neurologist, Charcot, further described the syndrome in 1868 (rigidity)----named ”Parkinson disease”. ▪ 1919: 确定病变部位主要在黑质 ▪ 1960: 发现与黑质纹状体中DA含量显著降低有关 每年的4月11日—— 世界帕金森病日