HUASHAN HOSPITA 莘山院 t hat percent of Canadians have hypertension 60 50 40 EO8 30 20 10 18-2425-3435-4444-55566565-74 age CCHS CMAJ 1992
What percent of Canadians have hypertension? 0 10 20 30 40 50 60 18-24 25-34 35-44 44-55 56-65 65-74 age % of Canadians CCHS CMAJ 1992
HUASHAN HOSPITA 莘山院 International Collaborative Study of t Cardiovascular Disease in ASIA(InterASIA) 27 2% of the Chinese adult population age 35 to 74 years has hypertension The percentage of those with hypertension who were aware(44.7%), treated ( 28. 2%), and controlled (8.1%)was unacceptably low
International Collaborative Study of Cardiovascular Disease in ASIA (InterASIA) 27.2% of the Chinese adult population age 35 to 74 years has hypertension The percentage of those with hypertension who were aware(44.7% ), treated(28.2% ), and controlled(8.1% ) was unacceptably low
HUASHAN HOSPITA 莘山院 ypertension Remains One of the Most Important factors of cv risk BP>140/90 mm Hg is associated with: 91% 77% 74% 69% 0% 209 60% 80% 100% First Mis Current CHF First Strokes Eventual chF BP, blood pressure; CHF, congestive heart failure; MI, myocardial infarction Rosamond w et al. Circulation. 2007: 115: 1-103
Hypertension Remains One of the Most Important factors of CV Risk BP >140/90 mm Hg is associated with: 69% 74% 77% 91% 0% 20% 40% 60% 80% 100% First MIs Current CHF First Strokes Eventual CHF 277,000 deaths in 2003 Rosamond W et al. Circulation. 2007;115:1-103. BP, blood pressure; CHF, congestive heart failure; MI, myocardial infarction
HUASHAN HOSPITA 莘山院 MECHANISMS OF ESSENTIAL HYPERTENSION (1) Genetic Predisposition --one of the most common complex genetic disorder Genetic heritability 30%
MECHANISMS OF ESSENTIAL HYPERTENSION (1) Genetic Predisposition --one of the most common complex genetic disorder Genetic heritability 30%
HUASHAN HOSPITA 莘山院 MECHANISMS OF ESSENTIAL HYPERTENSION (2) Environment -salt intake, obesity, occupation alcohol intake, crowding
Environment – salt intake, obesity, occupation, alcohol intake, crowding. MECHANISMS OF ESSENTIAL HYPERTENSION (2)