Interstitial Lung Diseases Yang,Dong(杨冬) yang dong @zs-hospitalshcn Department of Pulmonary medicine, Zhongshan Hospital, Fudan Universtiy
Interstitial Lung Diseases Yang，Dong (杨冬) yang.dong@zs-hospital.sh.cn Department of Pulmonary Medicine, Zhongshan Hospital, Fudan Universtiy
Definition a group of disease which predominantly affect the pulmonary connective tissue and interstitium (between the air sacs of the lungs) of the alveolar walls and share a common response of the lung to injury: alveolitis; inflammation; fibrosis of the interalveolar septum also known as"interstitial pulmonary fibrosis or diffuse parenchymal lung disease dpld)
Definition a group of disease which predominantly affect the pulmonary connective tissue and interstitium (between the air sacs of the lungs) of the alveolar walls and share a common response of the lung to injury: alveolitis; inflammation; fibrosis of the interalveolar septum also known as―interstitial pulmonary fibrosis‖or ―diffuse parenchymal lung disease (DPLD)‖
Common clinical feature 1. Exertional dyspnea or nonproductive cough 2. Tachypnea and bibasilar end-inspiratory dry cracks 3. Bilateral diffuse infiltrates on chest radiographs 4. Presents as a rEStRICTIVE lung disease DLcol, PA2O2↑ 5. Varying degrees of fibrosis and inflammation, with or without evidence of granulomatous or secondary vascular changes
Common clinical feature 1. Exertional dyspnea or nonproductive cough 2. Tachypnea and bibasilar end-inspiratory dry cracks 3. Bilateral diffuse infiltrates on chest radiographs 4. Presents as a RESTRICTIVE lung disease, DLco↓, PA-aO2↑ 5. Varying degrees of fibrosis and inflammation, with or without evidence of granulomatous or secondary vascular changes
What is the cause of ILD? ◆>180 kinds Chief known cause(1/3) Inhale inorganic dusts Inhale organic dusts P RadIo-active injury Micro-organic infection Drugs > Lymphocytic carcinoma Pulmonary edema
What is the cause of ILD? >180 kinds Chief known cause (1/3) Inhale inorganic dusts Inhale organic dusts Radio-active injury Micro-organic infection Drugs Lymphocytic carcinoma Pulmonary edema
What is the cause of IlD? 今 Chief unknown cause >Primary lung diseases >ILD associated with system disorder(Ctds) >Alveolar filling disorder >ILD associated with pulmonary vasculitis >Inherited disorders
What is the cause of ILD? Chief unknown cause Primary lung diseases ILD associated with system disorder (CTDs) Alveolar filling disorder ILD associated with pulmonary vasculitis Inherited disorders