Pneumonia Yuanlin Song, M.D. Department of Pulmonary medicine, Fudan university
Yuanlin Song, M.D. Department of Pulmonary Medicine, Fudan University
Definition and classification o Pneumonia: inflammation and consolidation of lung tissue due to an intectious agent. o Category: community acquired pneumonia(Cap)and hospital-acquired pneumonia(hapy e hap divided into ventilator associated pneumonia (VAP) or Non-ventilator Associated Pneumonia
Pneumonia: inflammation and consolidation of lung tissue due to an infectious agent. Category: community acquired pneumonia (CAP) and hospital-acquired pneumonia (HAP) HAP divided into Ventilator Associated Pneumonia (VAP) or Non-ventilator Associated Pneumonia
Pathogens Bacillus Pseudomonas Clostridium Escherichia ght c 2004 Denis Kunkel M Spirulina Staphylococcus Streptococcus salmonella http://www.denniskunkel.com/
Bacillus Pseudomonas Clostridium Escherichia Spirulina Staphylococcus Streptococcus Salmonella http://www.denniskunkel.com/
Host defense mechanism ◆ Upper-airway (nasal turbinates (2)mucocillary transport system: ciliary, mucus layer, IgA, mucosal pH, colonization of non-pathogenic bacteria ◆ Lower airway (1)glottis, cough, 2)innate immunity: macrophages, lysozymes, lactoferrin IgG, defensins, complement, cathelicidins, collectins ()epithelial barrier and antimicrobial peptide (4)specific host defense: T lymphocyte
Upper- airway: (1)nasal turbinates, (2)mucocillary transport system: ciliary, mucus layer, sIgA, mucosal pH, colonization of non-pathogenic bacteria Lower airway: (1)glottis, cough, (2)innate immunity: macrophages, lysozymes, lactoferrin, IgG, defensins, complement, cathelicidins, collectins (3)epithelial barrier and antimicrobial peptide (4)specific host defense: T lymphocyte
Anatomical structure of airway mucus mucus layer Liquid ciliary mucosa〈Gob| et cel 19 Submucosal gla
ciliary mucus Liquid Submucosal gland Goblet cell mucus layer mucosa