(3)Pleuropulmonary manifestation a diffuse interstitial fibrosis abnormal on ct scan. restrictive diffuse pattern( pulmonary function a intrapulmonary nodules:: asymptomatic, infected, cavitate o rheumatoid pleural disease exudative WBC<5 000/mm3 lower level of glucose -(4)pericarditis: 30%pericardial effusion, asymptomatic (5)gastrointestinal manifestation: D nausea, loss of appetite (6) kidney drug-induced, amyloid degeneration
（3） Pleuropulmonary manifestation diffuse interstitial fibrosis: abnormal on CT scan, restrictive diffuse pattern （pulmonary function ） intrapulmonary nodules:：asymptomatic, infected, cavitate rheumatoid pleural disease：exudative, WBC<5 000/mm3 , lower level of glucose (4）pericarditis: 30% pericardial effusion, asymptomatic （5）gastrointestinal manifestation: nausea, loss of appetite （6）kidney：drug-induced，amyloid degeneration
(7)Neurologic manifestations D atlantoaxial subluxation: sensory abnormity and loss of streng sth a peripheral neuropathies (8)Felty's syndrome consists of chronic RA, splenomegaly neutropenia, anemia and thrombocytopenia. It is most common in individuals with long-standing disease and high titers of rheumatoid factor
（7）Neurologic manifestations： atlantoaxial subluxation: sensory abnormity and loss of strength peripheral neuropathies （8）Felty’s syndrome ： consists of chronic RA, splenomegaly, neutropenia, anemia and thrombocytopenia. It is most common in individuals with long-standing disease and high titers of rheumatoid factor