卡前列素Carboprost,PGF2a HQ HO Carboprost is a synthetic prostaglandin analogue of PGF2 a (specifically,it is 15- methyl-PGF2 a)with oxytocic properties. Carboprost induces contractions and can trigger abortion in early pregnancy.It also reduces postpartum bleeding. Synthesis and inhibition of leukotrienes Leukcyte LTE LTD Leukocytes PLA Zleuton S9g→tca 5-poxygenase acid Gi-LCAMP BLT, Inhibition at the 5-LOX level and at the receptor level
卡前列素 Carboprost, PGF2α Carboprost is a synthetic prostaglandin analogue of PGF2α (specifically, it is 15- methyl-PGF2α) with oxytocic properties. Carboprost induces contractions and can trigger abortion in early pregnancy. It also reduces postpartum bleeding. Synthesis and inhibition of leukotrienes Inhibition at the 5-LOX level and at the receptor level
扎鲁司特Zafirlukast 孟鲁司特Montelukast (Singulair) Montelukast is a CysLT1 antagonist;that it blocks the action of leukotriene D4 (and secondary ligands LTC4 and LTE4)on the cysteinyl leukotriene receptor CysLT1 in the lungs and bronchial tubes by binding to it.This reduces the bronchoconstriction otherwise caused by the leukotriene and results in less inflammation. 齐留通Zileuton NH2 5-lipoxygenase inhibitor Zileuton(introduced in 1996 by Abbott Laboratories)is an active oral inhibitor of the enzyme 5-lipoxygenase,which forms leukotrienes from arachidonic acid.Zileuton is indicated for the prophylaxis and chronic treatment of asthma in adults and children 12 years of age and older. Zileuton is not indicated for use in the reversal of bronchospasm in acute asthma attacks.Therapy with zileuton can be continued during acute exacerbations of asthma
扎鲁司特 Zafirlukast 孟鲁司特 Montelukast (Singulair) Montelukast is a CysLT1 antagonist; that it blocks the action of leukotriene D4 (and secondary ligands LTC4 and LTE4) on the cysteinyl leukotriene receptor CysLT1 in the lungs and bronchial tubes by binding to it. This reduces the bronchoconstriction otherwise caused by the leukotriene and results in less inflammation. 齐留通 Zileuton Zileuton (introduced in 1996 by Abbott Laboratories) is an active oral inhibitor of the enzyme 5-lipoxygenase, which forms leukotrienes from arachidonic acid. Zileuton is indicated for the prophylaxis and chronic treatment of asthma in adults and children 12 years of age and older. Zileuton is not indicated for use in the reversal of bronchospasm in acute asthma attacks. Therapy with zileuton can be continued during acute exacerbations of asthma. 5-lipoxygenase inhibitor