Stages of chronic renal failure 1.Silent GFR up to 50 ml/min. 2.Renal insufficiency GFR 25 to 50 ml/min. 3.Renal failure -GFR 5 to 25 ml/min ● 4.End-stage renal failure GFR less than 5 ml/min
Stages of chronic renal failure • 1. Silent – GFR up to 50 ml/min. • 2. Renal insufficiency – GFR 25 to 50 ml/min. • 3. Renal failure – GFR 5 to 25 ml/min • 4. End-stage renal failure – GFR less than 5 ml/min
III.Cause of chronic renal failure Chronic renal failure(CRF)can be classified by the site (location)of primary damage: Pre-renal CRF Post-renal CRF (obstructive uropathy) Renal CRF
Ⅲ.Cause of chronic renal failure • Chronic renal failure (CRF) can be classified by the site (location) of primary damage: Pre-renal CRF Post-renal CRF (obstructive uropathy) Renal CRF
·Pre-Renal CRF Some medical conditions cause continuous hypoperfusion (low blood flow)of the kidneys,leading to kidney atrophy (shrinking),loss of nephron function,and chronic renal failure (CRF).These conditions include poor cardiac function, chronic liver failure,and atherosclerosis ("hardening")of the renal arteries.Each of these conditions can induce ischemic nephropathy
• Pre-Renal CRF Some medical conditions cause continuous hypoperfusion (low blood flow) of the kidneys, leading to kidney atrophy (shrinking), loss of nephron function, and chronic renal failure (CRF). These conditions include poor cardiac function, chronic liver failure, and atherosclerosis ("hardening") of the renal arteries. Each of these conditions can induce ischemic nephropathy
·Post-Renal CRF Interference with the normal flow of urine can produce backpressure within the kidneys,can damage nephrons,and lead to obstructive uropathy,a disease of the urinary tract.Abnormalities that may hamper urine flow and cause post-renal CRF include the following:
• Post-Renal CRF Interference with the normal flow of urine can produce backpressure within the kidneys, can damage nephrons, and lead to obstructive uropathy, a disease of the urinary tract. Abnormalities that may hamper urine flow and cause post-renal CRF include the following:
obstructive uropathy Kidney Ureter Bladder Urethra
obstructive uropathy