2.Two classes of membrane transport proteins transported molecule channel protein transporter lipid concentration bilayer gradient simple channel- transporter- diffusion mediated mediated PASSIVE TRANSPORT ACTIVE TRANSPORT Carrier proteins can carry out both passive and active transport. Channel proteins can only carry out passive transport. This document is produced by trial version of Print2Flash.Visit www.print2flash.com for more information
Carrier Proteins solute stateA state B OUTSIDE lipid concentration bilayer gradient INSIDE transporter mediating solute-binding site passive transport Carrier proteins bind one or more solute molecules on one side of the membrane and then undergo a conformational change that transfer the solute to the other side of the membrane. This document is produced by trial version of Print2Flash.Visit www.print2flash.com for more information
Carrier Proteins Carrier protein-mediated: Facilitated diffusion: 1)Bind with solute specifically and change the conformation; 2)Diffusion rate is influenced by the concentration gradient and the number of carrier protein; 3)Downhill,does not need ATP. Active transport: 1)Uphill,need ATP; 2)The carrier has the specificity and variability. This document is produced by trial version of Print2Flash.Visit www.print2flash.com for more information
Three types of carrier-mediated transport transported molecule co-transported ion lipid bilayer UNIPORT SYMPORT ANTIPORT coupled transport The schematic diagram shows carrier proteins functioning as uniports,symports,and antiports. This document is produced by trial version of Print2Flash.Visit www.print2flash.com for more information
3.Facilitate diffusion: Membrane transport protein mediated movement down the gradient ② OUTSIDE OF CELL Transport protein ① shifts to altemative ③ Glucose binds conformation Glucose is to binding site released to the open to outside inside and protein returns to its original Glucose conformation INSIDE OF CELL Glucose Glucose transporter (GluT1) The carrier protein,the Glucose transporter(GLUT1 )in the erythrocyte PM,alter conformation to facilitate the transport of glucose. This document is produced by trial version of Print2Flash.Visit www.print2flash.com for more information