Chapter 5 Analysis and Design of Biochemical Reactors
Chapter 5 Analysis and Design of Biochemical Reactors
Chapter 5 Analysis and Design of Biochemical reactors 5.cOncept of Design of Bioch. Reactors 5.1.cLassification Bioch. Reactors Batch Semi-Batch operation Continua operation operation Bio-block Reactors Bio-membrane reactors Full mix Plug flow Full mix Plug flow patter pattern pattern pattern, Stir tank Plug flow Fluid flow reactor Immobilized reactor reactor Cycle pipe reactor bio-disc Cycle reactor Bubble reactor Full mix membrane Leaching filter Loop reactor Multi-cascade reactor reactor Mem brane reacto
Chapter 5 Analysis and Design of Biochemical Reactors 5.1 Concept of Design of Bioch. Reactors 5.1.1Classification Bioch. Reactors Stir tank reactor Cycle reactor Loop reactor Plug flow reactor Bubble reactor Multi-cascade reactor Fluid flow reactor Cycle pipe reactor Full mix membrane reactor Immobilized bio-disc Leaching filter Membrane reactor Batch operation Semi-Batch operation Continual operation Bio-block Reactors Bio-membrane reactors Plug flow pattern Full mix pattern Full mix pattern Plug flow pattern
Diagram of Divers Enzymatic Reactors Operations 参阅《生化反应动力学与反应器》P285-290 Cycle Packed K immobilized X bed bed Batch Continuous Multi-cascade operation reactor 出切 ○ Multi-cascade semi- Stir vessel--super- operation Piping filter integration set P Coil immobilized Fluid flow Loop n membrane bed bed flow reactor reactor
Diagram of Divers Enzymatic Reactors & Operations 参阅《生化反应动力学与反应器》P285-290 Batch operation Continuous Multi-cascade reactor Fluid flow bed Stir vessel—superfilter integration set Multi-cascade semioperation Loop flow reactor Coil membrane reactor Packed bed Cycle immobilized bed Piping immobilized bed
5.1.2 Basic Equation for Design of Bio-Reaction (1) Mass balance(Accumulatn is o under steady state Calculation of Mass balance for substrates and products converted Input Output Accumulation components components components+ /unit of components /unit volume /unit volume /unit volume volume Calculation of mass balance for cells Input Output Grown Died cels cells cells Accumulate ceus /unit /unit /unit d cellls /unit /unit volume volume volume volume volume
5.1.2 Basic Equation for Design of Bio-Reaction （1）Mass balance（Accumulatn is 0 under steady state) Calculation of Mass balance for substrates and products Input components /unit volume = converted components /unit volume Output components /unit volume + + Accumulation of components /unit volume Grown cells /unit volume Accumulate d cells /unit volume Died cells /unit volume Output cells /unit volume Input cells /unit volume = + + + Calculation of Mass balance for cells
(2) Energy balance(Heat balance In a definite time: Reaction Input heat Output heat Accumulated heat /unit /unit time /unit time + heat /unit time time (3)Momentum balance It is usually negligible for bioreactors because of operation conducted under constant pressure. In conclusion each balance in the same model as follows: Input output consumption +accumulation
（2）Energy balance (Heat balance ) In a definite time: Input heat /unit time Output heat /unit time Reaction heat /unit time Accumulated = + + heat /unit time (3) Momentum balance It is usually negligible for bioreactors because of operation conducted under constant pressure. In conclusion, each balance in the same model as follows: Input = output + consumption +accumulation