2. Describe therapy method of Parkinsonism3. To grasp mechanism, therapeutic uses, adverse effects of Levodopa (L-dopa) and Carbidopa4. Know specific agents of treatment Parkinsonism5. Know definition of sedatives and hypnotics6.Knowtwo phases of sleep7. To grasp mechanism, therapeutic uses, adverse effects of diazepam8. Benzodiazepines Antagonist -------Flumazenil9. Describe mechanism, therapeutic uses, adverse effects of barbiturates10. Know other sedative-hypnotics11. Know the classification of affective disorders (Mania,depression)12. Know the mechanism of depression13. To grasp mechanism, therapeutic uses, adverse effects of tricyclic antidepressants14. Selective 5-HT Reuptake Inhibitors15. Describe Selective MAO-A inhibitor16. Know treatment of bipolar affective disorders (BPAD)17.Know basic concepts of psychotic disorders18. Know the dopamine theory for schizophrenia19. Know dopaminergic systems, dopamine receptors20.Know the classifications of neuroleptic drugs21. To grasp mechanism, therapeutic uses, adverse effects of phenothiazines22.Describe other phenothiazines23. Describe the antimanic drugs24. Describe the classification of the pain25. Describe classification of the opioid analgesics26. Describe mechanism of action of the opioid analgesics27. To grasp tolerance and physical dependence28. To grasp Organ system effects of morphine and its surrogates29. To grasp Clinical use of opioid analgesics30. To grasp toxicity and adverse reaction of opioid analgesics31. To grasp diagnosis and treatment of opioid overdosage32. Describe specific agents, meperidine
2. Describe therapy method of Parkinsonism 3. To grasp mechanism, therapeutic uses, adverse effects of Levodopa (L-dopa) and Carbidopa 4. Know specific agents of treatment Parkinsonism 5. Know definition of sedatives and hypnotics 6. Know two phases of sleep 7. To grasp mechanism, therapeutic uses, adverse effects of diazepam 8. Benzodiazepines Antagonist -Flumazenil 9. Describe mechanism, therapeutic uses, adverse effects of barbiturates 10. Know other sedative-hypnotics 11. Know the classification of affective disorders (Mania,depression) 12. Know the mechanism of depression 13. To grasp mechanism, therapeutic uses, adverse effects of tricyclic antidepressants 14. Selective 5-HT Reuptake Inhibitors 15. Describe Selective MAO-A inhibitor 16. Know treatment of bipolar affective disorders (BPAD) 17. Know basic concepts of psychotic disorders 18. Know the dopamine theory for schizophrenia 19. Know dopaminergic systems, dopamine receptors 20. Know the classifications of neuroleptic drugs 21. To grasp mechanism, therapeutic uses, adverse effects of phenothiazines 22. Describe other phenothiazines 23. Describe the antimanic drugs 24. Describe the classification of the pain 25. Describe classification of the opioid analgesics 26. Describe mechanism of action of the opioid analgesics 27. To grasp tolerance and physical dependence 28. To grasp Organ system effects of morphine and its surrogates 29. To grasp Clinical use of opioid analgesics 30. To grasp toxicity and adverse reaction of opioid analgesics 31. To grasp diagnosis and treatment of opioid overdosage 32. Describe specific agents, meperidine
33. Describe the opiod antagonist34.Describe classificationof epilepsy35.Describe mechanism of action of antiepileptic drugs36. To grasp therapeutic indications for anticonvulsant agents37. To grasp therapeutic uses, adverse effects of phenytoin, carbamazepine, phenobarbita38. Know other antiepileptic drugsLectures:Lecture 17: Treatment of Parkinson's Disease1.NeurotransmissionintheCNS1) Glutamate and aspartate2)-aminobutyric acid（GABA)3) Serotonin4) Acetylcholine5)Dopamine6) Norepinephrine7) Endorphins and enkephalins8)Other neurotransmitters:Dynorphins、Substance P, Nitric oxide(NO)2. Synaptic Potentials1) Excitatory Pathways2) Inhibitory Pathways3) Combined Effects of the EPSP and IPSP3. Overview of Parkinson's Disease4. Etiology: the loss of striatal dopamine produces an imbalance5. Levodopa (L-dopa) and Carbidopa1) Mechanism of Action2) Fate of Administered L-dopa3) Therapeutic Uses4) Adverse Effects5) Drug Interactions6) Contraindications6. Specific Agents
33. Describe the opiod antagonist 34. Describe classification of epilepsy 35. Describe mechanism of action of antiepileptic drugs 36. To grasp therapeutic indications for anticonvulsant agents 37. To grasp therapeutic uses, adverse effects of phenytoin, carbamazepine, phenobarbital 38. Know other antiepileptic drugs ◆Lectures: Lecture 17: Treatment of Parkinson’s Disease 1. Neurotransmission in the CNS 1) Glutamate and aspartate 2) γ-aminobutyric acid （GABA） 3) Serotonin 4) Acetylcholine 5) Dopamine 6) Norepinephrine 7) Endorphins and enkephalins 8) Other neurotransmitters: Dynorphins 、Substance P, Nitric oxide (NO) 2. Synaptic Potentials 1) Excitatory Pathways 2) Inhibitory Pathways 3) Combined Effects of the EPSP and IPSP 3. Overview of Parkinson’s Disease 4. Etiology: the loss of striatal dopamine produces an imbalance 5. Levodopa (L-dopa) and Carbidopa 1) Mechanism of Action 2) Fate of Administered L-dopa 3) Therapeutic Uses 4) Adverse Effects 5) Drug Interactions 6) Contraindications 6. Specific Agents
1)DopamineAgonists:Bromocriptine2) Monoamine oxidase inhibitors: rasagiline3)Catechol-O-Methyl Transferase Inhibitors :tolcapone and entacapone4) Anticholinergic Drugs1.Definition of Sedatives and Hypnotics2.Two phases of sleep3.Benzodiazepines-------Diazepam1)Classification2)Pharmacokinetics 3)Mechanism of benzodiazepines4) Therapeutic Uses5) Adverse Effects6)Tolerance and Dependence7) Drug Interactions8) Characteristics of different drugs4. Benzodiazepines Antagonist ---Flumazenil5.Barbiturates1)Classification2) Pharmacokinetics3) Mechanism of benzodiazepines4) Therapeutic Uses5)Adverse Effects6. Other Sedative-HypnoticsLecture 19: Antidepressants drugs1.Theclassification of affectivedisorders(Mania,depression)2.themechanismofdepression1)Monoamine theoryof depression2) The other theory of depression3. Tricyclic AntidepressantsD)Pharmacologiceffectsandmechanismofaction2)Clinical uses3) Side effects Tetracyclic
1) Dopamine Agonists : Bromocriptine 2) Monoamine oxidase inhibitors: rasagiline 3) Catechol-O-Methyl Transferase Inhibitors :tolcapone and entacapone 4) Anticholinergic Drugs 1. Definition of Sedatives and Hypnotics 2. Two phases of sleep 3. Benzodiazepines-Diazepam 1) Classification 2) Pharmacokinetics 3) Mechanism of benzodiazepines 4) Therapeutic Uses 5) Adverse Effects 6) Tolerance and Dependence 7) Drug Interactions 8) Characteristics of different drugs 4. Benzodiazepines Antagonist -Flumazenil 5. Barbiturates 1) Classification 2) Pharmacokinetics 3) Mechanism of benzodiazepines 4) Therapeutic Uses 5) Adverse Effects 6. Other Sedative-Hypnotics Lecture 19: Antidepressants drugs 1. The classification of affective disorders(Mania,depression) 2. the mechanism of depression 1) Monoamine theory of depression 2) The other theory of depression 3. Tricyclic Antidepressants 1) Pharmacologic effects and mechanism of action 2) Clinical uses 3) Side effects Tetracyclic