Pyrogens Neuroimmunoendocrine Substances that can cause fever Either exogenous or endogenous
Pyrogens •Neuroimmunoendocrine •Substances that can cause fever •Either exogenous or endogenous
Exogenous Pyrogens ● From outside the host (some may be the endogenous products) majority are microorganism, their products or toxins G: endotoxin(内毒素) ( lipopolysaccaride,LPS)(脂多糖) G lipoteichoic acid(脂磷壁酸) peptidoglycan 肽聚糖) varies superantigens and enterotoxins
Exogenous Pyrogens •From outside the host (some may be the endogenous products) •Majority are microorganism, their products or toxins G- : endotoxin(内毒素） (lipopolysaccaride, LPS) （脂多糖） G+ : lipoteichoic acid （脂磷壁酸） peptidoglycan（肽聚糖） varies superantigens and enterotoxins