A new science·Biochemistry is ayoung science.Most of the information included in this bookhas been uncovered inthe last 50 years (go through much further than the last 50 years).KnowledgeisaccumulatedGainabetterunderstandingof basicbiological systems and howtheyfunction·Researchtechniqueshavebeendeveloped-betterunderstandthese systemsTechniques growin process.>Science & methods used to elucidate and study science
A new science • Biochemistry is a young science • Most of the information included in this book has been uncovered in the last 50 years (go through much further than the last 50 years). • Gain a better understanding of basic biological systems and how they function • Research techniques have been developed - better understand these systems Science & methods used to elucidate and study science Techniques grow in process. Knowledge is accumulated
ThesignificanceofBiochemistrythe capacityto explain living systems atthemolecularlevel: A thorough understanding of each molecule's physical structure andchemical reactivity helps to lead to an understanding of how moleculescooperate and combine to form large functional units and, ultimately,theintactorganismOrganelleOrganMoleculeOrganism(function)Large cell
The significance of Biochemistry — the capacity to explain living systems at the molecular level • A thorough understanding of each molecule’s physical structure and chemical reactivity helps to lead to an understanding of how molecules cooperate and combine to form large functional units and, ultimately, the intact organism. Molecule Organelle Organ (function) Large cell Organism
Biochemical“Language"? Need unambiguous way to refer to certain molecules and pathways.Useofconsistentterminology? Need unambiguous way to illustrate moleculesIllustrate3-dimentional molecules in2D space[aelani:n]AlanineCOO-H-CCH3NH(a)(b)Structural formulaSpace-filling model(atoms&bonds)Ball-and-stickmodel(size)(whichatomsandwhere)Conveys:atoms present, bonds connecting them, size, how they are arranged in 3D space
Biochemical “Language” • Need unambiguous way to refer to certain molecules and pathways. • Use of consistent terminology • Need unambiguous way to illustrate molecules Illustrate 3-dimentional molecules in 2D space Alanine Conveys: atoms present, bonds connecting them, size, how they are arranged in 3D space ['æləniːn]
Biochemistryis...·Achemicalscience·Studyof structuresandtheirchemical interactions·Astudyinthermodynamics.TransformationofenergyintolivingmatterThese two aspects will be involved in almost every topic we will consider
Biochemistry is. • A chemical science • Study of structures and their chemical interactions • A study in thermodynamics • Transformation of energy into living matter These two aspects will be involved in almost every topic we will consider
RoleofBiochemistry·Unityofbiochemistry.Structures,mechanisms,and chemical processes shared by all organisms.E.coli.....human· Biochemical study elucidates the organizing principles of life inallitsdiverseforms·Biochemistry is ultimately concerned with the wonder of life itself
Role of Biochemistry • Unity of biochemistry • Structures, mechanisms, and chemical processes shared by all organisms • E.coli. human • Biochemical study elucidates the organizing principles of life in all its diverse forms • Biochemistry is ultimately concerned with the wonder of life itself