Lecture20HypersensitivityReactionsImmune responses that result in tissue injury
Immune-mediatedhypersensitivityreactionsTypeI-Anaphylactic/AtopicTypeII -CytotoxicType III -Toxic ComplexType IV -T-cell mediated
Immune-Mediated HypersensitivitiesTypeTypeITypeTypeVImmuneigEantbody.T,2ceilskGantbodykGantbodyTcellsreactantCerrmatix-Cel-assoaaledAntigenSoutie antigenSoubie antgenSautbie antigenassodatedantigenantigenCompiementCampiementEffectorMaaophageMast-olCyotoityFCRodlsPhagocytesmechanismactivatonactvaton(phagocytes,NK.olls)mmuneompexTbicod40VeSSEoomsmencomplemertLcytoknesExampleofAllergic rhinitis,SomedrugalergiesSerumsidness,Contaddematts.Coantaddematitistutbercuinreactionhypersensitivityastmasystemic(egpenidlin)Arthusreactianreactionanaphyaxis@1997CurrentBiology Ltd./GarlandPublishing,Inc
AnaphylacticlAtopicHypersensitivity(Type I)
AtopyDescribes theclinical features of individualswho developTypeIhypersensitivityincreased vascular permeabilitylocaledema-itchingStrong hereditary linkagesMediated by a serum factortermed"reagin'"Wheal and flare"reaction