产能途径 > EMP(Embden-Meyerhof-parans)途径 (糖酵解途径或二磷酸己糖途径) HMP途径(Hexose monophosphate)途径 磷酸戊糖途径或旁路)属循环途径 ( >ED途径(Entner-Doundoroff)途径 (2-酮-3脱氧-6-磷酸葡糖酸裂解途径) >TCA三羧酸循环
产能途径 ➢ EMP（Embden-Meyerhof-parans）途径 （糖酵解途径或二磷酸己糖途径） ➢ HMP途径（Hexose monophosphate）途径 （磷酸戊糖途径或旁路）属循环途径 ➢ ED途径（Entner-Doundoroff）途径 （2-酮-3脱氧-6-磷酸葡糖酸裂解途径） ➢ TCA 三羧酸循环
Glycolysis糖酵解途径 Glucose ATP- ADP Glucose 6-phosphate Six-carbon stage Fructose 6-phosphate ATP- ADP Fructose 1.6-bisphosphate Aldolase Glyceraldehyde-3-®→Dihydroxyacetone-p NAD P NADH +H' Three-carbon stage 1.3-bisphosphoglycerate ADP Substrate-level phosphorylation ATP 3-phosphoglycerate 2-phosphoglycerate 一*HO Phosphoenolpyruvate ADP Substrate-level phosphorylation ATP Pyruvate
Glycolysis 糖酵解途径
HIMP途径 3NADP 3NADPH+3H 3NADP' 3NADPH+3H' 3 glucose-6-P 3 6-phosphogluconate 3 nibulose-5-P) The transketolase reaction 3HO 3c0 0= H CH,OH CH,OH =0 0 H 9=0 -OH HO-C-H 0se-5-⊙ HO-C-H H-9 -OH + H-C-OH H-C-OH H-C-OH H- C-OH CH,o⊙ CHO P) CHO P) H-C-OH Glyceraldehyde 3-phosphate Xylulose Ribose CHO P) 5-phosphate 5-phosphate Glyceraldehyde-3-P) Sedoheptulose-7-P) Sedoheptulose 7-phosphate The transaldolase reaction Transaldolase CH,OH CHOH f=o H 9=o H Fructose-6-(P) Erythros 4-P) 5-(@ HO-C-H =0 0= H-C-OH H-C-OH→H-9-OH H-C-OH H-C-OH CH,O(P) H-C-OH H-C-OH Glyceraldehyde cHo⊙ CH,O P Fructose-6-(P) H-9-o州 3-phosphate CH.O(P) Fructose Erythrose 6-phosphate 4-phosphate Sedoheptulose 7-phosphate Fructose-6-P) Fructose-1,6-bis⊙
HMP途径
ED途径 Glucose K Glucose 6-phosphate NADP NADPH 6-phosphogluconate H.O 2-keto-3-deoxy-6-phosphogluconate Pyruvate Glyceraldehyde 3-phosphate NAD NADH ADP ATP ADP 1 ATP Pyruvate
ED途径
TCA Cycle Pyruvate -CoA NAD NADH+H C0, Acetyl-CoA(2 carbons) NADH +H' Oxaloacetate Citrate HO NAD Cis-aconitate L-Malate H.O 6 carbons ate 4 carbons NAD FADH FAD 5 carbons NADH H' -CO -Ketoglutarate CoASH CoASH NAD Succinyl-CoA NADH+H' GDP CO
TCA Cycle